VAMP3 and ACAP1

Number of citations of the paper that reports this interaction (PubMedID 15525538)
39

Data Source:
HPRD (in vitro, in vivo)

		VAMP3	ACAP1
Description		vesicle associated membrane protein 3	ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane Cell Surface Integral Component Of Membrane Apical Plasma Membrane Cell Junction Transport Vesicle Clathrin-coated Vesicle Secretory Granule Integral Component Of Synaptic Vesicle Membrane Clathrin-coated Vesicle Membrane Phagocytic Vesicle Membrane SNARE Complex Trans-Golgi Network Membrane Neuron Projection Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm Recycling Endosome Recycling Endosome Membrane	Membrane Recycling Endosome Membrane
	Molecular Function	SNAP Receptor Activity Protein Binding Syntaxin-1 Binding Syntaxin Binding	GTPase Activator Activity Protein Binding Metal Ion Binding
	Biological Process	Positive Regulation Of Receptor Recycling Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent Exocytosis Vesicle Docking Involved In Exocytosis Vesicle Fusion Vesicle-mediated Transport Calcium Ion Regulated Exocytosis Substrate Adhesion-dependent Cell Spreading SNARE Complex Assembly Retrograde Transport, Endosome To Golgi Golgi To Plasma Membrane Protein Transport Positive Regulation Of Immunoglobulin Secretion Membrane Organization Membrane Fusion Protein-containing Complex Assembly Mucus Secretion Cellular Response To Interferon-gamma Negative Regulation Of Secretion By Cell Regulation Of Histamine Secretion By Mast Cell	Protein Transport Positive Regulation Of GTPase Activity
Pathways		ER-Phagosome pathway Retrograde transport at the Trans-Golgi-Network Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis
Drugs
Diseases
GWAS		Crohn's disease ( 28067908 21102463) Inflammatory bowel disease ( 28067908) Morning vs. evening chronotype ( 26835600) Periodontal microbiota ( 22699663) Ulcerative colitis ( 28067908)
Interacting Genes		17 interacting genes: ACAP1 APP BCAP31 BCL2L13 DDB1 DNAJC5 IKBKG LMNA NELFE SNAP23 STX16 STX2 STX3 STX4 VAMP2 VAMP8 VEGFD	7 interacting genes: AKT1 GRB2 IFFO1 ITGB1 RABGAP1L TFRC VAMP3
Entrez ID		9341	9744
HPRD ID		04711	08474
Ensembl ID		ENSG00000049245	ENSG00000072818
Uniprot IDs		Q15836 Q6FGG2	Q15027
PDB IDs			3JUE 3T9K 4CKG 4CKH 4F1P 4NSW 5H3D
Enriched GO Terms of Interacting Partners?
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