VAMP3 and NELFE

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		VAMP3	NELFE
Description		vesicle associated membrane protein 3	negative elongation factor complex member E
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane Cell Surface Integral Component Of Membrane Apical Plasma Membrane Cell Junction Transport Vesicle Clathrin-coated Vesicle Secretory Granule Integral Component Of Synaptic Vesicle Membrane Clathrin-coated Vesicle Membrane Phagocytic Vesicle Membrane SNARE Complex Trans-Golgi Network Membrane Neuron Projection Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm Recycling Endosome Recycling Endosome Membrane	Nucleus Nucleoplasm Plasma Membrane Nuclear Body NELF Complex
	Molecular Function	SNAP Receptor Activity Protein Binding Syntaxin-1 Binding Syntaxin Binding	Chromatin Binding RNA Binding Protein Binding
	Biological Process	Positive Regulation Of Receptor Recycling Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent Exocytosis Vesicle Docking Involved In Exocytosis Vesicle Fusion Vesicle-mediated Transport Calcium Ion Regulated Exocytosis Substrate Adhesion-dependent Cell Spreading SNARE Complex Assembly Retrograde Transport, Endosome To Golgi Golgi To Plasma Membrane Protein Transport Positive Regulation Of Immunoglobulin Secretion Membrane Organization Membrane Fusion Protein-containing Complex Assembly Mucus Secretion Cellular Response To Interferon-gamma Negative Regulation Of Secretion By Cell Regulation Of Histamine Secretion By Mast Cell	Transcription By RNA Polymerase II Transcription Elongation From RNA Polymerase II Promoter Negative Regulation Of Transcription Elongation From RNA Polymerase II Promoter Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Viral Transcription Positive Regulation Of Histone H3-K4 Methylation Positive Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of MRNA Polyadenylation
Pathways		ER-Phagosome pathway Retrograde transport at the Trans-Golgi-Network Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis	Formation of RNA Pol II elongation complex Formation of the Early Elongation Complex Formation of HIV elongation complex in the absence of HIV Tat Formation of the HIV-1 Early Elongation Complex Formation of HIV-1 elongation complex containing HIV-1 Tat Formation of HIV-1 elongation complex containing HIV-1 Tat Pausing and recovery of Tat-mediated HIV elongation Abortive elongation of HIV-1 transcript in the absence of Tat Tat-mediated HIV elongation arrest and recovery Tat-mediated elongation of the HIV-1 transcript HIV elongation arrest and recovery Pausing and recovery of HIV elongation RNA Polymerase II Pre-transcription Events TP53 Regulates Transcription of DNA Repair Genes RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS		Crohn's disease ( 28067908 21102463) Inflammatory bowel disease ( 28067908) Morning vs. evening chronotype ( 26835600) Periodontal microbiota ( 22699663) Ulcerative colitis ( 28067908)	Asthma ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) Coronary artery disease ( 29212778) Disease progression in age-related macular degeneration ( 29346644) Inflammatory bowel disease ( 28067908) Ulcerative colitis ( 28067908) vWF levels ( 30586737)
Interacting Genes		17 interacting genes: ACAP1 APP BCAP31 BCL2L13 DDB1 DNAJC5 IKBKG LMNA NELFE SNAP23 STX16 STX2 STX3 STX4 VAMP2 VAMP8 VEGFD	10 interacting genes: CACTIN CCDC57 MTUS2 NCOR1 NELFB SRPK1 SRPK2 TNKS TRIM27 VAMP3
Entrez ID		9341	7936
HPRD ID		04711	01096
Ensembl ID		ENSG00000049245	ENSG00000204356
Uniprot IDs		Q15836 Q6FGG2	A0A1U9X830 P18615
PDB IDs			1X5P 2BZ2 2JX2 5OOB 6GML
Enriched GO Terms of Interacting Partners?
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