ACVR2B and SYNJ2BP

Number of citations of the paper that reports this interaction (PubMedID 11882656)
21

Data Source:
HPRD (two hybrid, in vitro)

		ACVR2B	SYNJ2BP
Description		activin A receptor type 2B	synaptojanin 2 binding protein
Image
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Protein-containing Complex Receptor Complex Activin Receptor Complex	Mitochondrion Ionotropic Glutamate Receptor Complex Basolateral Plasma Membrane Cell Junction Integral Component Of Mitochondrial Outer Membrane Neuromuscular Junction Neuron Projection Postsynaptic Density Membrane
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Serine/threonine/tyrosine Kinase Activity Protein Binding ATP Binding Activin Receptor Activity, Type II Activin-activated Receptor Activity Growth Factor Binding Metal Ion Binding Activin Binding	Protein Binding Protein C-terminus Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Gastrulation With Mouth Forming Second Kidney Development Lymphangiogenesis Blood Vessel Remodeling Regulation Of Transcription, DNA-templated Protein Phosphorylation Signal Transduction Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Determination Of Left/right Symmetry Mesoderm Development Heart Development Response To Glucose Post-embryonic Development Anterior/posterior Pattern Specification Insulin Secretion Lung Development Positive Regulation Of Bone Mineralization BMP Signaling Pathway Pancreas Development Activation Of Protein Kinase Activity Activin Receptor Signaling Pathway Positive Regulation Of Activin Receptor Signaling Pathway Organ Growth Odontogenesis Of Dentin-containing Tooth Positive Regulation Of Osteoblast Differentiation Embryonic Foregut Morphogenesis Skeletal System Morphogenesis Roof Of Mouth Development Lymphatic Endothelial Cell Differentiation Artery Development Venous Blood Vessel Development Retina Vasculature Development In Camera-type Eye Cellular Response To Growth Factor Stimulus Negative Regulation Of Cold-induced Thermogenesis	Negative Regulation Of Endothelial Cell Proliferation Protein Targeting Rho Protein Signal Transduction Chemical Synaptic Transmission Regulation Of Notch Signaling Pathway Embryo Development Negative Regulation Of Endothelial Cell Migration Negative Regulation Of Angiogenesis Regulation Of Endocytosis Receptor Clustering Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Intracellular Distribution Of Mitochondria Negative Regulation Of ERK1 And ERK2 Cascade Receptor Localization To Synapse Cell-cell Adhesion Negative Regulation Of Sprouting Angiogenesis
Pathways		Signaling by NODAL Regulation of signaling by NODAL Signaling by Activin Signaling by Activin Signaling by BMP
Drugs
Diseases		Heterotaxy; Situs ambiguus
GWAS		Bitter beverage consumption ( 31046077) Estimated glomerular filtration rate ( 31152163 31015462) P wave duration ( 24850809)	Blood pressure ( 24954895) LDL cholesterol ( 30275531) Normal facial asymmetry (angle of surface orientation score) ( 30631343)
Interacting Genes		21 interacting genes: ACVR1B BMP10 BMP2 BMP7 ERBIN FBXO7 GDF11 GDF2 GDF5 IGSF1 INHBA INHBB INHBC MSTN NODAL SNX1 SNX2 SNX6 SYNJ2BP TDGF1 TGFBRAP1	13 interacting genes: ACTB ACVR2A ACVR2B APP LRP1 LRP2 LRP8 RALBP1 RPS6KA1 SMOC1 SYNJ2 UBQLN1 USHBP1
Entrez ID		93	55333
HPRD ID		04106	15455
Ensembl ID		ENSG00000114739	ENSG00000213463
Uniprot IDs		Q13705	A0A024R670 P57105
PDB IDs		2H62 2QLU 4FAO 5NGV 5NHR	2ENO 2JIK 2JIN
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?