HNRNPLL and THAP1

Number of citations of the paper that reports this interaction (PubMedID 26871637)
108

Data Source:
BioGRID (two hybrid)

		HNRNPLL	THAP1
Description		heterogeneous nuclear ribonucleoprotein L like	THAP domain containing 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Membrane	Nuclear Chromatin Fibrillar Center Nucleus Nucleoplasm PML Body Intracellular Membrane-bounded Organelle
	Molecular Function	RNA Binding MRNA Binding Protein Binding	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Protein Binding Zinc Ion Binding Identical Protein Binding Protein Homodimerization Activity Sequence-specific DNA Binding
	Biological Process	MRNA Processing Regulation Of Translation Positive Regulation Of RNA Splicing Regulation Of RNA Splicing	Negative Regulation Of Transcription By RNA Polymerase II Endothelial Cell Proliferation Transcription, DNA-templated Regulation Of Transcription, DNA-templated Cell Cycle Regulation Of Mitotic Cell Cycle
Pathways
Drugs
Diseases			Primary torsion dystonia (PTD)
GWAS		Body mass index ( 28892062)	Pelvic organ prolapse (moderate/severe) ( 26545240)
Interacting Genes		41 interacting genes: ADAMTSL4 ATXN1 BANP BARD1 BHLHE40 BOLL CALCOCO2 DAB1 DDX39A DDX39B EFHC2 FAM9B GOPC HNRNPK IKZF3 KHDRBS2 KRT31 KRT40 KRTAP10-3 MAGED1 MDFI MID2 PAXIP1 PCBP1 PNMA1 RBM10 RBPMS REL RHOXF2 SKIL SPRY2 SRSF11 SSX2IP TADA2A THAP1 TLE5 TMCC2 TRIM23 TRIM27 UBE2I VAC14	65 interacting genes: ABCF3 ACOT7 AEBP2 AKAP17A AKAP9 AP2B1 APP ARL6IP4 BAG5 BMS1P1 BYSL C1orf35 C7orf50 CHD2 CSNK2A1 DCAF8 DVL2 EEF1AKNMT FAM124A FAM133A FXR2 GOLGA7 GPATCH2L HNRNPLL KLF12 KRTAP10-7 LASP1 MORF4L1 MORF4L2 MRPL11 NKAP NKAPD1 NTAQ1 NUP62 PAWR PHF1 PID1 POLR2L POLR2M PPIG PRKAA1 PRR20A QKI RALYL RBM10 RBM39 RIPPLY1 RP9P RPS25 SAP30BP SERF2 SLU7 STRBP TCEA2 TPM3 TRAF5 TRIM26 TTLL10 TXN2 U2AF2 WT1 YES1 ZCCHC10 ZNF385C ZNF408
Entrez ID		92906	55145
HPRD ID		13667	15496
Ensembl ID		ENSG00000143889	ENSG00000131931
Uniprot IDs		A0A0S2Z6K1 A8K894 Q8WVV9	Q9NVV9
PDB IDs			2JTG 2KO0 2L1G
Enriched GO Terms of Interacting Partners?
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