THAP1 and GOLGA7

		THAP1	GOLGA7
Description		THAP domain containing 1	golgin A7
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Fibrillar Center Nucleus Nucleoplasm PML Body Intracellular Membrane-bounded Organelle	Golgi Membrane Palmitoyltransferase Complex Extracellular Region Golgi Stack Intrinsic Component Of Golgi Membrane Extracellular Exosome Tertiary Granule Lumen
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Protein Binding Zinc Ion Binding Identical Protein Binding Protein Homodimerization Activity Sequence-specific DNA Binding	Protein Binding Protein-cysteine S-palmitoyltransferase Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Endothelial Cell Proliferation Transcription, DNA-templated Regulation Of Transcription, DNA-templated Cell Cycle Regulation Of Mitotic Cell Cycle	Protein Targeting To Membrane Golgi To Plasma Membrane Transport Peptidyl-L-cysteine S-palmitoylation Golgi To Plasma Membrane Protein Transport Neutrophil Degranulation Protein Stabilization
Pathways			Neutrophil degranulation
Drugs
Diseases		Primary torsion dystonia (PTD)
GWAS		Pelvic organ prolapse (moderate/severe) ( 26545240)	Metabolite levels ( 23823483)
Interacting Genes		65 interacting genes: ABCF3 ACOT7 AEBP2 AKAP17A AKAP9 AP2B1 APP ARL6IP4 BAG5 BMS1P1 BYSL C1orf35 C7orf50 CHD2 CSNK2A1 DCAF8 DVL2 EEF1AKNMT FAM124A FAM133A FXR2 GOLGA7 GPATCH2L HNRNPLL KLF12 KRTAP10-7 LASP1 MORF4L1 MORF4L2 MRPL11 NKAP NKAPD1 NTAQ1 NUP62 PAWR PHF1 PID1 POLR2L POLR2M PPIG PRKAA1 PRR20A QKI RALYL RBM10 RBM39 RIPPLY1 RP9P RPS25 SAP30BP SERF2 SLU7 STRBP TCEA2 TPM3 TRAF5 TRIM26 TTLL10 TXN2 U2AF2 WT1 YES1 ZCCHC10 ZNF385C ZNF408	10 interacting genes: ACTN2 GOLGA3 LSM1 PLPBP POMK PPP1CC RNF170 TCIM THAP1 TPT1P8
Entrez ID		55145	51125
HPRD ID		15496	13595
Ensembl ID		ENSG00000131931	ENSG00000147533
Uniprot IDs		Q9NVV9	Q7Z5G4
PDB IDs		2JTG 2KO0 2L1G
Enriched GO Terms of Interacting Partners?
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