GORAB and RCHY1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid, in vitro, in vivo)

		GORAB	RCHY1
Description		golgin, RAB6 interacting	ring finger and CHY zinc finger domain containing 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Nucleolus Cytoplasm Golgi Apparatus Cytosol	Ubiquitin Ligase Complex Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Speck Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding	P53 Binding Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Protein Homodimerization Activity
	Biological Process	Hair Follicle Morphogenesis Positive Regulation Of Smoothened Signaling Pathway Involved In Dorsal/ventral Neural Tube Patterning Non-motile Cilium Assembly	Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Positive Regulation Of Protein Ubiquitination Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Error-free Translesion Synthesis
Pathways			Translesion Synthesis by POLH Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases		Geroderma osteodysplasticum
GWAS		Atrial fibrillation ( 29892015) Heel bone mineral density ( 30598549) Male-pattern baldness ( 27182965 28196072) Waist-hip ratio ( 25673412) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500) Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500) Waist-to-hip ratio adjusted for BMI in inactive individuals ( 28448500) Waist-to-hip ratio adjusted for BMI in non-smokers ( 28443625) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971) Waist-to-hip ratio adjusted for body mass index ( 25673412 28448500)	Metabolite levels ( 23823483) Response to tocilizumab in rheumatoid arthritis ( 22491018)
Interacting Genes		18 interacting genes: APP ARF1 ARF3 ARF5 BET1L COPB1 FARSA FBXO7 HOXD9 HSD17B7 MDM2 NEDD4L NKG7 PTAFR RAB6A RCHY1 SCYL1 ZNF16	69 interacting genes: ADAMTSL4 AIG1 ANGPTL8 AOX1 AR ARF4 ATN1 BIRC3 CAMK2A CAMK2G CDK9 CDKN1B CHD8 CHEK2 COPE COX6C CYBA DAPK1 DCUN1D5 F7 FADS6 GFI1B GORAB HOXA2 HOXB1 HOXB5 HOXC4 HRG KAT5 KLHL41 KRTAP9-2 LIMS2 MDM2 MEOX2 MSH3 MT2A NKD2 NLK NOTCH2NLA PGLS PLAGL2 PMM1 PRDX4 RAB11A RBM38 RILP RPLP1 RPN2 SEMA4C SERPINA1 SERPINA5 SERTAD1 SRPRB TAOK2 TMBIM1 TMEM14C TMEM184A TP53 TP63 TP73 TRIM8 UBASH3B UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 WDR74 ZNF160
Entrez ID		92344	25898
HPRD ID		12144	07607
Ensembl ID		ENSG00000120370	ENSG00000163743
Uniprot IDs		B3KQ87 Q5T7V8	Q96PM5
PDB IDs			2JRJ 2K2C 2K2D
Enriched GO Terms of Interacting Partners?
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