ACVR2A and MAGI2

  • Number of citations of the paper that reports this interaction (PubMedID 10681527)
  • 26
  • Data Source:
  • HPRD (two hybrid, in vitro)

ACVR2A

MAGI2

Description activin A receptor type 2A membrane associated guanylate kinase, WW and PDZ domain containing 2
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Acute lymphoblastic leukemia (childhood) ( 23007406)
  • Adverse response to drug ( 30420678)
  • Airway wall thickness ( 25517131)
  • Bitter beverage consumption ( 31046077)
  • Body mass index ( 28892062 25673413)
  • Bronchopulmonary dysplasia ( 23897914)
  • Chronotype ( 30696823)
  • Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444)
  • Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes ( 29221444)
  • General risk tolerance (MTAG) ( 30643258)
  • Hippocampal atrophy ( 19668339)
  • Itch intensity from mosquito bite adjusted by bite size ( 28199695)
  • LDL cholesterol levels x short total sleep time interaction (1df test) ( 31719535)
  • LDL cholesterol levels x short total sleep time interaction (2df test) ( 31719535)
  • Lead levels in blood ( 25820613)
  • Mammographic density (dense area) ( 25342443)
  • Memory dysfunction in frontotemporal lobe dementia ( 29724592)
  • Metabolite levels ( 23823483)
  • Night sleep phenotypes ( 27126917)
  • Obesity-related traits ( 23251661)
  • Pursuit maintenance gain ( 29064472)
  • Response to anti-depressant treatment in major depressive disorder ( 22041458)
  • Schizophrenia ( 28991256 30285260)
  • Serum folate levels ( 29953918)
  • Visceral fat ( 30942860)
Interacting Genes 23 interacting genes: ACVRL1 BMP10 BMP2 BMP4 BMP6 BMP7 DAXX ENG ERBIN GDF2 GDF5 GDF9 IGSF1 INHBA INHBB INHBC MAGI2 NODAL PRSS50 SYNJ2BP TCTEX1D4 TDGF1 TGFBR3 17 interacting genes: ACVR2A ADGRB1 ADRB1 ARRDC3 ATN1 CRHR1 CTNNB1 CTNND2 DLL1 DSCAML1 GRID2 PLXNB3 PTEN RAPGEF2 RPS6KA1 SMAD3 TGFA
Entrez ID 92 9863
HPRD ID 00025 16212
Ensembl ID ENSG00000121989 ENSG00000187391
Uniprot IDs P27037 B7Z4H4 Q86UL8
PDB IDs 3Q4T 3SOC 4ASX 5NH3 1UEP 1UEQ 1UEW 1UJV 1WFV
Enriched GO Terms of Interacting Partners?
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