DEDD and HOXD4

Number of citations of the paper that reports this interaction (PubMedID 20211142)
329

Data Source:
BioGRID (two hybrid)

		DEDD	HOXD4
Description		death effector domain containing	homeobox D4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleolus Cytoplasm	Nuclear Chromatin Nucleus Nucleoplasm Cell Junction
	Molecular Function	DNA Binding Protein Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Activating Transcription Factor Binding
	Biological Process	Spermatogenesis Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Regulation Of Apoptotic Process	Skeletal System Development Multicellular Organism Development Anterior/posterior Pattern Specification Positive Regulation Of Transcription By RNA Polymerase II Embryonic Skeletal System Morphogenesis
Pathways			Activation of anterior HOX genes in hindbrain development during early embryogenesis
Drugs
Diseases
GWAS			Estimated glomerular filtration rate ( 31015462) Male-pattern baldness ( 28196072) Obstructive sleep apnea trait (apnea hypopnea index) ( 29077507) Pelvic organ prolapse (moderate/severe) ( 26545240)
Interacting Genes		16 interacting genes: APLP2 APP BATF2 CASP10 CASP3 CASP8 CFLAR DEDD2 FADD GTF3C1 GTF3C3 HOXD4 KRT18 KRT8 SHMT1 SMAD3	19 interacting genes: ASB8 CNOT7 CREBBP DEDD EP300 ETV4 HIPK1 HNRNPAB HOXB13 MEIS1 PBX1 RNPS1 RXRG SNAI1 TIGD4 XRCC6 ZBTB32 ZMYND11 ZSCAN18
Entrez ID		9191	3233
HPRD ID		06022	00864
Ensembl ID		ENSG00000158796	ENSG00000170166
Uniprot IDs		B1AQP5 O75618	P09016
PDB IDs
Enriched GO Terms of Interacting Partners?
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