PCSK7 and SYNCRIP

Number of citations of the paper that reports this interaction (PubMedID 11051545)
113

Data Source:
HPRD (in vivo)

		PCSK7	SYNCRIP
Description		proprotein convertase subtilisin/kexin type 7	synaptotagmin binding cytoplasmic RNA interacting protein
Image		No pdb structure
GO Annotations	Cellular Component	Trans-Golgi Network Membrane Integral Component Of Golgi Membrane	Nucleus Nucleoplasm Endoplasmic Reticulum Membrane CRD-mediated MRNA Stability Complex Catalytic Step 2 Spliceosome Histone Pre-mRNA 3'end Processing Complex GAIT Complex Ribonucleoprotein Complex
	Molecular Function	Serine-type Endopeptidase Activity Peptidase Activity	RNA Binding MRNA Binding Protein Binding Poly(A) Binding MRNA 5'-UTR Binding
	Biological Process	Protein Processing Peptide Hormone Processing	MRNA Splicing, Via Spliceosome Osteoblast Differentiation RNA Processing RNA Splicing Viral Process Negative Regulation Of Translation CRD-mediated MRNA Stabilization Cellular Response To Interferon-gamma
Pathways
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488 28240269) Cardiovascular disease risk factors ( 21943158) HDL cholesterol ( 31170924 24507774) Iron status biomarkers ( 21149283) Triglyceride levels ( 26763881) Triglycerides ( 24507774)
Interacting Genes		6 interacting genes: CSDE1 HNRNPD HSPA5 PABPC1 PMCH SYNCRIP	31 interacting genes: A1CF APOBEC1 APP CSDE1 EPRS1 ESR1 GRB2 HABP4 HMGA1 HMGA2 HNRNPD HNRNPK IL7R INSR IVNS1ABP KLHL3 NUPR1 PABPC1 PCSK7 PLCG1 PRMT1 PTPN11 SMN1 SYT1 SYT11 SYT2 SYT3 SYT4 SYT7 SYT8 SYT9
Entrez ID		9159	10492
HPRD ID		05339	06734
Ensembl ID		ENSG00000160613	ENSG00000135316
Uniprot IDs		Q16549	B7Z645 O60506 Q59GL1
PDB IDs			2DGU 2MXT 2NBB
Enriched GO Terms of Interacting Partners?
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