SYNCRIP and SYT4

Number of citations of the paper that reports this interaction (PubMedID 10734137)
26

Data Source:
HPRD (in vivo, in vitro)

		SYNCRIP	SYT4
Description		synaptotagmin binding cytoplasmic RNA interacting protein	synaptotagmin 4
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Endoplasmic Reticulum Membrane CRD-mediated MRNA Stability Complex Catalytic Step 2 Spliceosome Histone Pre-mRNA 3'end Processing Complex GAIT Complex Ribonucleoprotein Complex	Plasma Membrane Integral Component Of Golgi Membrane Integral Component Of Synaptic Vesicle Membrane Axon Dendrite Dense Core Granule Membrane Neuron Projection Neuronal Cell Body Intracellular Membrane-bounded Organelle Neuron Projection Terminus Synapse Perinuclear Region Of Cytoplasm Exocytic Vesicle Astrocyte Projection Glutamatergic Synapse Neuronal Dense Core Vesicle Integral Component Of Neuronal Dense Core Vesicle Membrane Microvesicle
	Molecular Function	RNA Binding MRNA Binding Protein Binding Poly(A) Binding MRNA 5'-UTR Binding	SNARE Binding Phosphatidylserine Binding Calcium Ion Binding Protein Binding Calcium-dependent Phospholipid Binding Syntaxin-1 Binding Clathrin Binding Syntaxin-3 Binding Protein Homodimerization Activity Protein Heterodimerization Activity
	Biological Process	MRNA Splicing, Via Spliceosome Osteoblast Differentiation RNA Processing RNA Splicing Viral Process Negative Regulation Of Translation CRD-mediated MRNA Stabilization Cellular Response To Interferon-gamma	Vesicle Fusion Neurotransmitter Secretion Brain Development Memory Positive Regulation Of Glutamate Secretion Regulation Of Dopamine Secretion Vesicle-mediated Transport Calcium Ion Regulated Exocytosis Regulation Of Calcium Ion-dependent Exocytosis Regulation Of Endocytosis Negative Regulation Of Vesicle Fusion Negative Regulation Of Catecholamine Secretion Negative Regulation Of Calcium Ion-dependent Exocytosis Positive Regulation Of Calcium Ion-dependent Exocytosis Negative Regulation Of Short-term Neuronal Synaptic Plasticity Negative Regulation Of Protein Secretion Vesicle Fusion With Vesicle Secretory Granule Maturation Cellular Response To Calcium Ion Regulation Of Presynaptic Dense Core Granule Exocytosis Trans-synaptic Signaling By BDNF, Modulating Synaptic Transmission Dense Core Granule Cytoskeletal Transport Positive Regulation Of Dendrite Extension Negative Regulation Of Dense Core Granule Exocytosis Positive Regulation Of Dense Core Granule Exocytosis Negative Regulation Of Retrograde Trans-synaptic Signaling By Neuropeptide Negative Regulation Of Synaptic Vesicle Exocytosis
Pathways
Drugs
Diseases
GWAS			Accelerometer-based physical activity measurement (average acceleration) ( 29899525) Body mass index ( 28892062 25673413) Coffee consumption ( 31046077) Metabolite levels ( 23823483) Parkinson's disease ( 28892059 21738487) Physical activity (moderate intensity activity duration) ( 30531941) Physical activity (overall physical activity time) ( 30531941) Plasma proprotein convertase subtilisin/kexin type 9 levels in stable coronary artery disease ( 29748315) Pulse pressure ( 27841878) Pyoderma gangrenosum in inflammatory bowel disease ( 24487271) Squamous cell lung carcinoma ( 28604730) Systolic blood pressure ( 27841878)
Interacting Genes		31 interacting genes: A1CF APOBEC1 APP CSDE1 EPRS1 ESR1 GRB2 HABP4 HMGA1 HMGA2 HNRNPD HNRNPK IL7R INSR IVNS1ABP KLHL3 NUPR1 PABPC1 PCSK7 PLCG1 PRMT1 PTPN11 SMN1 SYT1 SYT11 SYT2 SYT3 SYT4 SYT7 SYT8 SYT9	10 interacting genes: NBR1 NRXN1 SGTA STX1A STX2 STX3 STX4 SYNCRIP SYT1 TFAP2B
Entrez ID		10492	6860
HPRD ID		06734	02519
Ensembl ID		ENSG00000135316	ENSG00000132872
Uniprot IDs		B7Z645 O60506 Q59GL1	Q9H2B2
PDB IDs		2DGU 2MXT 2NBB	1UGK
Enriched GO Terms of Interacting Partners?
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