CBFA2T2 and PDP1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		CBFA2T2	PDP1
Description		CBFA2/RUNX1 partner transcriptional co-repressor 2	pyruvate dehyrogenase phosphatase catalytic subunit 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Mitochondrion Mitochondrial Matrix
	Molecular Function	DNA-binding Transcription Factor Activity Transcription Corepressor Activity Protein Binding Metal Ion Binding	Protein Serine/threonine Phosphatase Activity Magnesium-dependent Protein Serine/threonine Phosphatase Activity [pyruvate Dehydrogenase (lipoamide)] Phosphatase Activity Protein Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Neuron Projection Development Negative Regulation Of Neuron Projection Development Negative Regulation Of Notch Signaling Pathway Negative Regulation Of Transcription, DNA-templated Intestinal Epithelial Cell Differentiation	Regulation Of Acetyl-CoA Biosynthetic Process From Pyruvate Peptidyl-threonine Dephosphorylation Positive Regulation Of Pyruvate Dehydrogenase Activity
Pathways			Regulation of pyruvate dehydrogenase (PDH) complex
Drugs
Diseases			Pyruvate dehydrogenase complex deficiency; X-linked Leigh syndrome
GWAS		Height ( 28552196)
Interacting Genes		22 interacting genes: APP ATN1 ATXN1L CBFA2T3 CBFB FBXL19 GTF2E1 ID3 LBP MDFI NCOR1 NCOR2 NEUROG1 NOTCH3 NTAQ1 PDP1 RERE RUNX1 SIN3A TAL2 TCP1 ZNF652	8 interacting genes: ACAT1 CBFA2T2 EGFR FGFR1 PDHA1 PLEKHF2 PRKCD SIRT3
Entrez ID		9139	54704
HPRD ID		04721	16185
Ensembl ID		ENSG00000078699	ENSG00000164951
Uniprot IDs		O43439	A0A024R9C0 Q6P1N1 Q9P0J1
PDB IDs
Enriched GO Terms of Interacting Partners?
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