SART1 and MFAP1

Number of citations of the paper that reports this interaction (PubMedID 22365833)
132

Data Source:
BioGRID (two hybrid, two hybrid)

		SART1	MFAP1
Description		spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP	microfibril associated protein 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Cytosol Cajal Body Nuclear Speck U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome Catalytic Step 2 Spliceosome	Microfibril Extracellular Region Nucleus Nucleoplasm Centrosome U2-type Precatalytic Spliceosome
	Molecular Function	RNA Binding Protein Binding	RNA Binding Protein Binding
	Biological Process	Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome Maturation Of 5S RRNA MRNA Cis Splicing, Via Spliceosome Positive Regulation Of Cytotoxic T Cell Differentiation	MRNA Splicing, Via Spliceosome
Pathways		mRNA Splicing - Major Pathway	Molecules associated with elastic fibres
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Bipolar disorder ( 31043756) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634)	Lipoprotein phospholipase A2 activity in cardiovascular disease ( 28753643)
Interacting Genes		12 interacting genes: APP CHERP IGHE MFAP1 PLAT SNW1 SRPK2 SRSF4 UBE2I UBL5 WBP4 ZCCHC10	47 interacting genes: AMOTL2 BEND7 CARD9 CCDC57 CDCA7L CEP55 CEP57L1 CEP70 COIL CSNK2A1 DHX38 DHX8 FAM9B FRA10AC1 FXR2 GKAP1 GOLGA2 HMBOX1 HSPB1 IK KATNBL1 KIFC3 KRT40 LDOC1 LMNA MAD1L1 MID2 MIPOL1 MTUS2 NDC80 PHC2 SART1 SNIP1 SNW1 SSX2IP STX11 TADA2A TLE5 TRIM42 TRIM54 U2AF1 VPS52 YWHAG ZBTB14 ZBTB8A ZFP64 ZNF398
Entrez ID		9092	4236
HPRD ID		10440	02569
Ensembl ID		ENSG00000175467	ENSG00000140259
Uniprot IDs		O43290	P55081
PDB IDs		4PYU 5O9Z 6AHD 6QW6 6QX9	5F5S 5O9Z 6AHD
Enriched GO Terms of Interacting Partners?
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