SART1 and CHERP

Number of citations of the paper that reports this interaction (PubMedID 22365833)
132

Data Source:
BioGRID (two hybrid, two hybrid)

		SART1	CHERP
Description		spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP	calcium homeostasis endoplasmic reticulum protein
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Cytosol Cajal Body Nuclear Speck U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome Catalytic Step 2 Spliceosome	Cell Nucleoplasm Cytoplasm Membrane Sarcoplasmic Reticulum Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	RNA Binding Protein Binding	RNA Binding Protein Binding Ion Channel Binding
	Biological Process	Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome Maturation Of 5S RRNA MRNA Cis Splicing, Via Spliceosome Positive Regulation Of Cytotoxic T Cell Differentiation	MRNA Splicing, Via Spliceosome Cellular Calcium Ion Homeostasis Nervous System Development Negative Regulation Of Cell Proliferation Release Of Sequestered Calcium Ion Into Cytosol Positive Regulation Of Calcineurin-NFAT Signaling Cascade
Pathways		mRNA Splicing - Major Pathway	mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Bipolar disorder ( 31043756) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634)
Interacting Genes		12 interacting genes: APP CHERP IGHE MFAP1 PLAT SNW1 SRPK2 SRSF4 UBE2I UBL5 WBP4 ZCCHC10	27 interacting genes: AGGF1 APBB1 ARGLU1 CCAR1 EWSR1 FRA10AC1 HNRNPH3 LUC7L PPIL4 PRPF38A PRPF40A RACK1 RBM23 RBM39 RBM7 RNPS1 SART1 SF3B4 SNIP1 SNRNP27 SNRNP70 SRPK1 SRPK2 TTC14 U2AF1 U2AF2 WBP4
Entrez ID		9092	10523
HPRD ID		10440	13051
Ensembl ID		ENSG00000175467	ENSG00000085872
Uniprot IDs		O43290	Q8IWX8
PDB IDs		4PYU 5O9Z 6AHD 6QW6 6QX9
Enriched GO Terms of Interacting Partners?
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