PKD2L1 and TNNI1

Number of citations of the paper that reports this interaction (PubMedID 12809519)
5

Data Source:
BioGRID (pull down)

		PKD2L1	TNNI1
Description		polycystin 2 like 1, transient receptor potential cation channel	troponin I1, slow skeletal type
Image			No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Membrane Integral Component Of Membrane Cytoplasmic Vesicle Calcium Channel Complex Intracellular Membrane-bounded Organelle Receptor Complex Ciliary Membrane Non-motile Cilium	Cytosol Troponin Complex
	Molecular Function	Calcium Activated Cation Channel Activity Cation Channel Activity Calcium Channel Activity Sodium Channel Activity Calcium Ion Binding Protein Binding Cytoskeletal Protein Binding Cation Transmembrane Transporter Activity Calcium-activated Potassium Channel Activity Sour Taste Receptor Activity Identical Protein Binding Muscle Alpha-actinin Binding Alpha-actinin Binding	Actin Binding Protein Binding Metal Ion Binding
	Biological Process	Detection Of Chemical Stimulus Involved In Sensory Perception Of Sour Taste Cation Transport Smoothened Signaling Pathway Response To Water Sodium Ion Transmembrane Transport Detection Of Chemical Stimulus Involved In Sensory Perception Of Taste Sensory Perception Of Sour Taste Detection Of Mechanical Stimulus Protein Homotetramerization Calcium Ion Transmembrane Transport Cellular Response To Acidic PH Potassium Ion Transmembrane Transport Inorganic Cation Transmembrane Transport	Skeletal Muscle Contraction Muscle Contraction Regulation Of Striated Muscle Contraction Transition Between Fast And Slow Fiber Muscle Filament Sliding Ventricular Cardiac Muscle Tissue Morphogenesis Cardiac Muscle Contraction
Pathways			Striated Muscle Contraction
Drugs
Diseases
GWAS		Coronary artery disease ( 29212778) Diastolic blood pressure ( 30224653) Fatty acid desaturase activity (adipose tissue) ( 30453627) Glycerophospholipid levels ( 26068415) Heel bone mineral density ( 30598549 28869591) Macular thickness ( 30535121) Mean platelet volume ( 27863252) Obesity-related traits ( 23251661) Palmitic acid (16:0) levels ( 23362303) Palmitoleic acid (16:1n-7) levels ( 28298293 23362303) Phospholipid levels (plasma) ( 22359512) Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1) ( 26503814) Serum metabolite levels ( 24625756) Serum metabolite levels (CMS) ( 31636271) Serum metabolite ratios in chronic kidney disease ( 29545352) Squamous cell lung carcinoma ( 28604730) Vaccenic acid (18:1n-7) levels ( 28298293)
Interacting Genes		4 interacting genes: CLDN19 TNNI1 TNNI2 TNNI3	10 interacting genes: ACTA1 CCDC85B MDFI PKD2L1 PNMA1 TNNC1 TNNT1 TNNT2 TRIM55 TRIM63
Entrez ID		9033	7135
HPRD ID		16063	01842
Ensembl ID		ENSG00000107593	ENSG00000159173
Uniprot IDs		Q1L4F0 Q9P0L9	P19237
PDB IDs		3TE3 4GIF 6DU8
Enriched GO Terms of Interacting Partners?
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