CCNG1 and LTBP3

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		CCNG1	LTBP3
Description		cyclin G1	latent transforming growth factor beta binding protein 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cyclin-dependent Protein Kinase Holoenzyme Complex Nucleus Nucleoplasm Cytoplasm	Extracellular Region Collagen-containing Extracellular Matrix Extracellular Exosome
	Molecular Function	Protein Kinase Activity Protein Binding Cyclin-dependent Protein Serine/threonine Kinase Regulator Activity Protein Kinase Binding	Calcium Ion Binding Transforming Growth Factor Beta Binding
	Biological Process	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Protein Phosphorylation Mitotic Cell Cycle Phase Transition Cell Division	Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Bone Mineralization Negative Regulation Of Chondrocyte Differentiation Transforming Growth Factor Beta Activation Positive Regulation Of Bone Resorption Bone Remodeling Bone Morphogenesis Lung Saccule Development Positive Regulation Of Mesenchymal Stem Cell Proliferation Positive Regulation Of Mesenchymal Stem Cell Differentiation
Pathways		Regulation of TP53 Degradation	Molecules associated with elastic fibres
Drugs
Diseases			Tooth agenesis; Hypodontia
GWAS		HIV progression (CD4 and viral load) ( 28132517) Metabolite levels ( 31628463) Plasma anti-thyroglobulin levels ( 29678681) Severe influenza A (H1N1) infection ( 26379185)	Acne (severe) ( 24927181) Heel bone mineral density ( 30598549) Non-alcoholic fatty liver disease histology (lobular) ( 20708005) Osteoarthritis (hip) ( 30374069) Urate levels ( 23263486) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
Interacting Genes		26 interacting genes: APP CBY2 CDK5 CDKN2A GAK GRN HMBOX1 KRT40 KRTAP10-7 LMNA LTBP3 LZTS2 MDM2 MT-CO2 NFATC4 PAK5 PLEKHA4 PNMA1 PPP2CA PTPA RBPMS SHKBP1 TFAP2C TFIP11 TNIP1 TP53	12 interacting genes: CACNA1A CCNG1 GORASP2 HBEGF ITGB5 PELI2 PIK3R2 PRPF40A RAC1 TGFB1 TGFB2 TGFB3
Entrez ID		900	4054
HPRD ID		03345	03649
Ensembl ID		ENSG00000113328	ENSG00000168056
Uniprot IDs		P51959	B9EG76 Q8WYU6 Q9NS15
PDB IDs
Enriched GO Terms of Interacting Partners?
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