CCNE1 and COIL

Number of citations of the paper that reports this interaction (PubMedID 10751146)
33

Data Source:
HPRD (in vitro)

		CCNE1	COIL
Description		cyclin E1	coilin
Image			No pdb structure
GO Annotations	Cellular Component	Cyclin-dependent Protein Kinase Holoenzyme Complex Nucleus Nucleoplasm Cytoplasm Centrosome Cytosol Cyclin E1-CDK2 Complex	Fibrillar Center Nucleus Nucleoplasm Nucleolus Cajal Body Membrane Nuclear Body
	Molecular Function	Transcription Coactivator Activity Protein Kinase Activity Protein Binding Cyclin-dependent Protein Serine/threonine Kinase Regulator Activity Protein Kinase Binding Androgen Receptor Binding	Protein Binding Protein C-terminus Binding U1 SnRNA Binding U2 SnRNA Binding Identical Protein Binding
	Biological Process	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity G1/S Transition Of Mitotic Cell Cycle Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Transcription By RNA Polymerase II Telomere Maintenance DNA Replication Initiation Protein Phosphorylation Synapsis Wnt Signaling Pathway Androgen Receptor Signaling Pathway Mitotic Cell Cycle Phase Transition Positive Regulation Of Transcription, DNA-templated Cell Division Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cellular Protein Localization	Spliceosomal SnRNP Assembly
Pathways		G0 and Early G1 SCF(Skp2)-mediated degradation of p27/p21 DNA Damage/Telomere Stress Induced Senescence Association of TriC/CCT with target proteins during biosynthesis TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest CDK-mediated phosphorylation and removal of Cdc6 Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes Cyclin E associated events during G1/S transition G1/S-Specific Transcription p53-Dependent G1 DNA Damage Response PTK6 Regulates Cell Cycle
Drugs
Diseases		Laryngeal cancer Gastric cancer
GWAS		Bladder cancer ( 24163127 20972438) Body mass index ( 25673413) Breast cancer ( 29058716) Breast cancer (estrogen-receptor negative) ( 29058716) Diastolic blood pressure ( 28135244 27841878) Medication use (diuretics) ( 31015401) Response to fenofibrate (total cholesterol levels) ( 27002377) Spatial processing ( 31596458)	Height ( 18391951)
Interacting Genes		68 interacting genes: AKT1 AR ARHGEF5 ARID4A ARIH1 ARNT AURKA BRCA2 BTRC CABLES1 CALM1 CCND2 CCT4 CDC25A CDC6 CDK1 CDK2 CDK3 CDK4 CDK6 CDKN1A CDKN2A CDKN2B CDKN2C COIL CUL3 FBXW7 FGFR4 FOXM1 FZR1 GLIS2 GRM1 GSK3B H1-0 H1-1 H1-5 HERC5 KAT2A LATS2 MARCKS MCM3 MRE11 MYBL2 MYC NBN NF2 PIN1 POLD1 PRC1 PRKAR1A PTPA RASSF1 RB1 RBL1 RBL2 REL RHOBTB3 RRN3 SKP2 SMARCA4 SMARCC1 SMARCD3 SPOP STK11 TERT TP73 TSC1 UBTF	70 interacting genes: ACTN1 ACTN2 ACTN4 APP ARMCX1 ATXN1 ATXN1L BYSL C1QBP CCDC136 CCDC159 CCNE1 CDC23 CDK2 CEP70 CEP76 CSNK2B CYB5R2 DHX16 DNAJA3 DRG1 ELOA2 FGF12 FHL5 FXR2 GCC1 KALRN KAZN KLC2 KLC4 KLHL42 KLHL8 KPNA3 LNX1 MAD1L1 MFAP1 MYO5B NIF3L1 NOLC1 NTAQ1 NUDT18 PDE4D PDLIM5 PIAS4 PICK1 PLEKHG4 POLR2L PREPL PRMT1 PRMT8 PSMA1 PSME3 PTS SART3 SCYL1 SMN1 SNRPB SNRPF SNX6 TAF9 TCAF1 TFCP2 TGS1 TSPYL2 WDR34 XRCC5 XRCC6 ZBTB25 ZCCHC10 ZNF277
Entrez ID		898	8161
HPRD ID		00455	02605
Ensembl ID		ENSG00000105173	ENSG00000121058
Uniprot IDs		A0A0G3DHS8 P24864 V5W5X2	P38432
PDB IDs		1W98 5L2W
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?