COIL and CEP70

Number of citations of the paper that reports this interaction (PubMedID 16713569)
313

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		COIL	CEP70
Description		coilin	centrosomal protein 70
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Fibrillar Center Nucleus Nucleoplasm Nucleolus Cajal Body Membrane Nuclear Body	Centrosome Cytosol
	Molecular Function	Protein Binding Protein C-terminus Binding U1 SnRNA Binding U2 SnRNA Binding Identical Protein Binding	Protein Binding Identical Protein Binding Gamma-tubulin Binding
	Biological Process	Spliceosomal SnRNP Assembly	G2/M Transition Of Mitotic Cell Cycle Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Microtubule Cytoskeleton Organization Ciliary Basal Body-plasma Membrane Docking
Pathways			Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs
Diseases
GWAS		Height ( 18391951)	Exhaled carbon monoxide levels in smokers with chronic obstructive pulmonary disease ( 29631575) Male-pattern baldness ( 28196072)
Interacting Genes		70 interacting genes: ACTN1 ACTN2 ACTN4 APP ARMCX1 ATXN1 ATXN1L BYSL C1QBP CCDC136 CCDC159 CCNE1 CDC23 CDK2 CEP70 CEP76 CSNK2B CYB5R2 DHX16 DNAJA3 DRG1 ELOA2 FGF12 FHL5 FXR2 GCC1 KALRN KAZN KLC2 KLC4 KLHL42 KLHL8 KPNA3 LNX1 MAD1L1 MFAP1 MYO5B NIF3L1 NOLC1 NTAQ1 NUDT18 PDE4D PDLIM5 PIAS4 PICK1 PLEKHG4 POLR2L PREPL PRMT1 PRMT8 PSMA1 PSME3 PTS SART3 SCYL1 SMN1 SNRPB SNRPF SNX6 TAF9 TCAF1 TFCP2 TGS1 TSPYL2 WDR34 XRCC5 XRCC6 ZBTB25 ZCCHC10 ZNF277	144 interacting genes: ABT1 AKAP17A ARHGEF3 ATP5PO ATXN7 BARD1 BEX2 BRMS1 BYSL C1orf35 C7orf25 C8orf33 CARD9 CCDC85B CDC73 CDCA7L CEP57L1 CFAP53 CLPB COIL DAZAP2 DDX41 DDX6 DNAJB11 ELOA ELOA2 EMD EMP1 ENKD1 ERCC3 FAM118B FAM124A FAM133A FAM13C FAM161A FAM214B GATAD2B GCC1 GPATCH2L GPATCH4 GPX7 HAUS1 HDAC6 HMGB4 HSPD1 IK IQCE KANK2 KANSL1 KAT7 KDM1A KRT31 LAMTOR5 LENG1 LENG8 LIN37 MCM10 MEST METTL17 MFAP1 MRPL44 NIPSNAP3A NKAP NKAPD1 NOL12 NOP2 NRIP1 NUSAP1 PAM16 PIBF1 PIMREG PLA2G2A PPFIA1 PPIG PPP1R16B PRKRIP1 PRPF31 PSMA1 RBM10 RCOR3 RHPN1 RNF6 RPL13 SERPINH1 SETD5 SFR1 SH2D4A SLU7 SMARCE1 SNRPD2 SRGN SSX3 STK25 STMN2 SUV39H1 SUV39H2 SYT17 SYTL4 SYTL5 TAF1D TEAD4 TRIM29 TRIM42 TSFM TSGA10IP TSHZ3 TTC25 TTLL10 TXLNB UTP11 UTP14A UTP25 WT1 YJU2 ZBTB16 ZBTB24 ZBTB49 ZBTB8A ZCCHC10 ZFC3H1 ZGPAT ZNF136 ZNF148 ZNF169 ZNF227 ZNF239 ZNF266 ZNF302 ZNF329 ZNF366 ZNF408 ZNF410 ZNF417 ZNF426 ZNF439 ZNF490 ZNF555 ZNF557 ZNF572 ZNF578 ZNF587 ZNF607 ZNF688 ZSCAN12
Entrez ID		8161	80321
HPRD ID		02605	16779
Ensembl ID		ENSG00000121058	ENSG00000114107
Uniprot IDs		P38432	A0A140VJG2 B7Z2D2 Q8NHQ1
PDB IDs
Enriched GO Terms of Interacting Partners?
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