TRIM24 and CBX1

Number of citations of the paper that reports this interaction (PubMedID 10562550)
137

Data Source:
HPRD (in vitro)

		TRIM24	CBX1
Description		tripartite motif containing 24	chromobox 1
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nuclear Euchromatin Perichromatin Fibrils Cytosol	Chromosome, Centromeric Region Nuclear Chromosome, Telomeric Region Chromatin Female Pronucleus Male Pronucleus Nucleus Nucleoplasm Nuclear Heterochromatin Pericentric Heterochromatin Spindle Chromocenter Site Of DNA Damage
	Molecular Function	P53 Binding Chromatin Binding Transcription Coactivator Activity Protein Kinase Activity Ubiquitin-protein Transferase Activity Signaling Receptor Binding Protein Binding Zinc Ion Binding Nuclear Receptor Binding Estrogen Response Element Binding Methylated Histone Binding Ubiquitin Protein Ligase Activity Lysine-acetylated Histone Binding	Chromatin Binding Protein Binding Enzyme Binding Identical Protein Binding Histone Methyltransferase Binding
	Biological Process	Transcription By RNA Polymerase II Negative Regulation Of Cell Proliferation Protein Ubiquitination Protein Catabolic Process Regulation Of Protein Stability Regulation Of Apoptotic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Protein Autophosphorylation Calcium Ion Homeostasis Regulation Of Vitamin D Receptor Signaling Pathway Cellular Response To Estrogen Stimulus Regulation Of Signal Transduction By P53 Class Mediator	Cellular Response To DNA Damage Stimulus Negative Regulation Of Transcription, DNA-templated
Pathways		Signaling by cytosolic FGFR1 fusion mutants Signaling by FGFR1 in disease Signaling by BRAF and RAF fusions	HCMV Early Events
Drugs
Diseases
GWAS		Disease progression in age-related macular degeneration (adjusted for baseline) ( 29346644) Quantitative traits ( 19197348)	Body mass index ( 26426971 20935630) Generalized epilepsy ( 22949513)
Interacting Genes		50 interacting genes: AR ATF4 BRCA1 BRD7 CBX1 CBX3 CBX5 ESR1 ESR2 FBN2 FOSL1 GTF2E1 H3C10 H3C11 H3C12 H3C2 H3C3 H3C4 H3C6 H3C7 H3C8 HNF4A HSPA1A HSPB1 MTNR1B NFE2L2 NR2F2 NR3C1 NR3C2 PGR PML PPARG RARA RNF141 RNF181 RXRA STAT6 SUMO1 TAF11 TAF1B TAF1C TAF7 THRA TRIM28 TRIM33 TRIM8 UBE2I UBE2U VDR ZNF10	34 interacting genes: ABI3BP ARL5A BARD1 BRCA1 CBX3 CBX5 CHAF1A DCAF7 DNMT1 DNMT3A DNMT3B EMSY H1-4 H3-4 H3C1 H3C3 HECW2 HSPB1 KLF11 LRIF1 NR2F6 NSL1 PCNA PIM1 RB1 RPL12 SP100 SUV39H1 TBKBP1 TRIM24 TRIM28 UCHL1 VHL VTN
Entrez ID		8805	10951
HPRD ID		04556	05149
Ensembl ID		ENSG00000122779	ENSG00000108468
Uniprot IDs		A0A024R784 O15164	P83916 Q6IBN6
PDB IDs		2YYN 3O33 3O34 3O35 3O36 3O37 4YAB 4YAD 4YAT 4YAX 4YBM 4YBS 4YBT 4YC9 4ZQL 5H1T 5H1U 5H1V	2FMM 3F2U 3Q6S 5T1G 6D07 6D08
Enriched GO Terms of Interacting Partners?
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