ACTN2 and GRIN2B

  • Number of citations of the paper that reports this interaction (PubMedID 9009191)
  • 168
  • Data Source:
  • HPRD (in vivo)

ACTN2

GRIN2B

Description actinin alpha 2 glutamate ionotropic receptor NMDA type subunit 2B
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adventurousness ( 30643258)
  • Aging (time to event) ( 21782286)
  • Alzheimer's disease in hypertension ( 31055733)
  • Brain structure (temporal lobe volume) ( 20197096)
  • Cellular nuclear factor (erythroid-derived 2)-like 2 levels ( 30767168)
  • Cerebrospinal AB1-42 levels in normal cognition ( 29274321)
  • Cognitive performance ( 19734545)
  • Egg allergy (parent-of-origin effect) ( 29489655)
  • General risk tolerance (MTAG) ( 30643258)
  • Height ( 31562340)
  • Immune reponse to smallpox (secreted IL-2) ( 22610502)
  • Major depressive disorder ( 23377640)
  • Ovarian reserve ( 22116950)
  • Response to selective serotonin reuptake inhibitors in depression ( 30034349)
  • Spherical equivalent or myopia (age of diagnosis) ( 29808027)
  • Systolic blood pressure ( 30224653)
  • Total ventricular volume ( 21116278)
  • Waist-hip ratio ( 28552196)
  • Waist-to-hip ratio adjusted for BMI ( 28552196)
Interacting Genes 86 interacting genes: ACTN1 ACTN3 ADAM12 ADORA2A AKAP8L ANG ANGPTL7 ATP5MC1 ATXN2 ATXN7 BRMS1L CAMK2A CAMK2D CAMK2G CAPN1 CD27 CLEC4D COIL CRABP2 CRADD DISC1 DLG1 DLG4 EPS8L1 ERBIN FAM50B FBXL22 GATA3 GOLGA7 GRIN1 GRIN2B GSTT1 H4C9 HSPB1 ITGB3BP KAT2B KATNAL2 KCNA4 KCNA5 KCNN2 LDB3 LRP12 LRRC7 MED14 MICALL2 MOS MRPL10 MYOT MYOZ1 MYOZ2 MYOZ3 MYPN NCAPH2 NCOA2 NCOR1 NOS3 NR1I2 NRIP1 PALLD PDLIM1 PDLIM3 PKD2 PPP1CB QARS1 RACK1 RAVER1 RPL35 RTP5 SAXO1 SELE SNAI1 SNW1 SP100 SPA17 SRP9 SSX2IP ST7 SYNPO2 TCTEX1D2 TNN TOLLIP TTN UTRN ZC2HC1C ZNF446 ZNRD2 40 interacting genes: ACTN2 AP1M1 AP2M1 AP4M1 ARHGAP32 CAMK2A CAMK2B CAMK2D CAMK2G CAMK2N1 CAPN1 DLG1 DLG2 DLG3 DLG4 EPHB2 ERBIN EXOC4 EXOC7 FYN GRIN1 GRIN3A IL16 LIN7A LIN7B MAGI3 MIB2 PATJ PIK3CA PLCG1 PRKCA PRKCB PRKCG PRKN PTPN11 RACK1 SPTAN1 SRC SYNGAP1 TANC1
Entrez ID 88 2904
HPRD ID 00019 00697
Ensembl ID ENSG00000077522 ENSG00000273079
Uniprot IDs F6THM6 P35609 Q59FD9 Q13224
PDB IDs 1H8B 1HCI 1QUU 4D1E 5A36 5A37 5A38 5A4B 1S11 1S2S 2IPV 5EWJ 5EWL 5EWM
Enriched GO Terms of Interacting Partners?
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