EIF3D and DNAJB11

Number of citations of the paper that reports this interaction (PubMedID 21900206)
114

Data Source:
BioGRID (two hybrid)

		EIF3D	DNAJB11
Description		eukaryotic translation initiation factor 3 subunit D	DnaJ heat shock protein family (Hsp40) member B11
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Eukaryotic Translation Initiation Factor 3 Complex Membrane Eukaryotic 43S Preinitiation Complex Eukaryotic 48S Preinitiation Complex Eukaryotic Translation Initiation Factor 3 Complex, EIF3m	Endoplasmic Reticulum Endoplasmic Reticulum Lumen Membrane
	Molecular Function	RNA Binding Translation Initiation Factor Activity Protein Binding MRNA Cap Binding	Protein Binding Unfolded Protein Binding
	Biological Process	Formation Of Cytoplasmic Translation Initiation Complex Cap-dependent Translational Initiation Translational Initiation Positive Regulation Of Translation IRES-dependent Viral Translational Initiation Viral Translational Termination-reinitiation Positive Regulation Of MRNA Binding	Protein Folding Positive Regulation Of ATPase Activity IRE1-mediated Unfolded Protein Response Protein Maturation
Pathways		L13a-mediated translational silencing of Ceruloplasmin expression Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit	XBP1(S) activates chaperone genes
Drugs
Diseases
GWAS			Blood protein levels ( 30072576)
Interacting Genes		13 interacting genes: BEND5 CREBBP DNAJB11 EIF3G EIF3J EIF3L EIF5 HOMER3 LZTS2 PHLDA1 REL SAT1 TRIM27	24 interacting genes: ANKZF1 AP2M1 APOBEC1 BAG6 CEP70 COL6A1 CRMP1 DDAH2 DNAJC13 DRAP1 EIF3D EZH2 FAF1 GRB2 HSPA1A PAXIP1 PTN SIMC1 SNX5 SPRED1 SUMO4 UBQLN4 UBR1 ZZZ3
Entrez ID		8664	51726
HPRD ID		04888	07485
Ensembl ID		ENSG00000100353	ENSG00000090520
Uniprot IDs		O15371	Q9UBS4
PDB IDs
Enriched GO Terms of Interacting Partners?
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