EIF3D and EIF3L

Number of citations of the paper that reports this interaction (PubMedID 11590142)
15

Data Source:
HPRD (in vitro)

		EIF3D	EIF3L
Description		eukaryotic translation initiation factor 3 subunit D	eukaryotic translation initiation factor 3 subunit L
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Eukaryotic Translation Initiation Factor 3 Complex Membrane Eukaryotic 43S Preinitiation Complex Eukaryotic 48S Preinitiation Complex Eukaryotic Translation Initiation Factor 3 Complex, EIF3m	Fibrillar Center Nucleoplasm Cytosol Eukaryotic Translation Initiation Factor 3 Complex Membrane Eukaryotic 43S Preinitiation Complex Eukaryotic 48S Preinitiation Complex
	Molecular Function	RNA Binding Translation Initiation Factor Activity Protein Binding MRNA Cap Binding	RNA Binding Translation Initiation Factor Activity Protein Binding
	Biological Process	Formation Of Cytoplasmic Translation Initiation Complex Cap-dependent Translational Initiation Translational Initiation Positive Regulation Of Translation IRES-dependent Viral Translational Initiation Viral Translational Termination-reinitiation Positive Regulation Of MRNA Binding	Formation Of Cytoplasmic Translation Initiation Complex Translational Initiation Viral Translational Termination-reinitiation
Pathways		L13a-mediated translational silencing of Ceruloplasmin expression Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit	L13a-mediated translational silencing of Ceruloplasmin expression Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit
Drugs
Diseases
GWAS
Interacting Genes		13 interacting genes: BEND5 CREBBP DNAJB11 EIF3G EIF3J EIF3L EIF5 HOMER3 LZTS2 PHLDA1 REL SAT1 TRIM27	10 interacting genes: DNM2 EIF3D EIF3E EIF3K HRAS POLR1B RGS2 RRN3 SMAD2 XRN2
Entrez ID		8664	51386
HPRD ID		04888	10932
Ensembl ID		ENSG00000100353	ENSG00000100129
Uniprot IDs		O15371	Q9Y262
PDB IDs			3J8B 3J8C 6FEC
Enriched GO Terms of Interacting Partners?
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