CADPS and PIP5K1A

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
HPRD (two hybrid)

		CADPS	PIP5K1A
Description		calcium dependent secretion activator	phosphatidylinositol-4-phosphate 5-kinase type 1 alpha
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Cell Junction Presynapse Glutamatergic Synapse Neuronal Dense Core Vesicle Membrane	Nucleus Nucleoplasm Cytosol MRNA Cleavage And Polyadenylation Specificity Factor Complex Plasma Membrane Focal Adhesion Nuclear Speck Lamellipodium Ruffle Membrane
	Molecular Function	Protein Binding Lipid Binding Protein Kinase Binding Metal Ion Binding	Protein Binding ATP Binding 1-phosphatidylinositol-4-phosphate 5-kinase Activity Kinase Binding
	Biological Process	Exocytosis Protein Transport Synaptic Vesicle Exocytosis Positive Regulation Of Exocytosis Dense Core Granule Exocytosis	Glycerophospholipid Metabolic Process Phosphatidylinositol Biosynthetic Process Phagocytosis Signal Transduction Phospholipid Biosynthetic Process Fibroblast Migration Regulation Of Phosphatidylinositol 3-kinase Signaling Cell Migration Keratinocyte Differentiation Actin Cytoskeleton Reorganization Phosphatidylinositol Phosphorylation Focal Adhesion Assembly Cell Chemotaxis Protein Localization To Plasma Membrane Activation Of GTPase Activity Ruffle Assembly
Pathways			Synthesis of PIPs at the plasma membrane PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
Drugs		Calcium Citrate Calcium Phosphate
Diseases
GWAS		Autism spectrum disorder ( 30804558) Breast size ( 22747683 27182965) Cognitive decline rate in late mild cognitive impairment ( 26252872) Economic and political preferences (environmentalism) ( 22566634) Hand grip strength ( 29691431) Lung function (FEV1/FVC) ( 30061609) Metabolite levels (X-11787) ( 23934736) Obsessive-compulsive symptoms ( 26859814) Optic disc size ( 31809533) Pre-treatment viral load in HIV-1 infection ( 31219150) QT interval (sulfonylurea treatment interaction) ( 27958378) Risk-taking tendency (4-domain principal component model) ( 30643258) Thiopurine-induced leukopenia in inflammatory bowel disease ( 29923122) Trunk fat mass ( 28552196)	Body mass index ( 26426971)
Interacting Genes		15 interacting genes: C17orf67 DMD DNAJC5 DRD2 FAM161A FAM9B KIAA1549 LUC7L2 PIP5K1A SDCBP SHFL TCL1A TTLL10 ZNF572 ZNF688	14 interacting genes: APP ARF1 ARF5 ARF6 BTK CADPS CASP3 KRAS NEDD4 PIP5KL1 PLD1 PLD2 RHOU TEC
Entrez ID		8618	8394
HPRD ID		05236	04470
Ensembl ID		ENSG00000163618	ENSG00000143398
Uniprot IDs		F1T0E5 Q9ULU8	A6PW57 Q99755
PDB IDs		1WI1
Enriched GO Terms of Interacting Partners?
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