PIP5K1A and CADPS

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
HPRD (two hybrid)

		PIP5K1A	CADPS
Description		phosphatidylinositol-4-phosphate 5-kinase type 1 alpha	calcium dependent secretion activator
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol MRNA Cleavage And Polyadenylation Specificity Factor Complex Plasma Membrane Focal Adhesion Nuclear Speck Lamellipodium Ruffle Membrane	Cytosol Cell Junction Presynapse Glutamatergic Synapse Neuronal Dense Core Vesicle Membrane
	Molecular Function	Protein Binding ATP Binding 1-phosphatidylinositol-4-phosphate 5-kinase Activity Kinase Binding	Protein Binding Lipid Binding Protein Kinase Binding Metal Ion Binding
	Biological Process	Glycerophospholipid Metabolic Process Phosphatidylinositol Biosynthetic Process Phagocytosis Signal Transduction Phospholipid Biosynthetic Process Fibroblast Migration Regulation Of Phosphatidylinositol 3-kinase Signaling Cell Migration Keratinocyte Differentiation Actin Cytoskeleton Reorganization Phosphatidylinositol Phosphorylation Focal Adhesion Assembly Cell Chemotaxis Protein Localization To Plasma Membrane Activation Of GTPase Activity Ruffle Assembly	Exocytosis Protein Transport Synaptic Vesicle Exocytosis Positive Regulation Of Exocytosis Dense Core Granule Exocytosis
Pathways		Synthesis of PIPs at the plasma membrane PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
Drugs			Calcium Citrate Calcium Phosphate
Diseases
GWAS		Body mass index ( 26426971)	Autism spectrum disorder ( 30804558) Breast size ( 22747683 27182965) Cognitive decline rate in late mild cognitive impairment ( 26252872) Economic and political preferences (environmentalism) ( 22566634) Hand grip strength ( 29691431) Lung function (FEV1/FVC) ( 30061609) Metabolite levels (X-11787) ( 23934736) Obsessive-compulsive symptoms ( 26859814) Optic disc size ( 31809533) Pre-treatment viral load in HIV-1 infection ( 31219150) QT interval (sulfonylurea treatment interaction) ( 27958378) Risk-taking tendency (4-domain principal component model) ( 30643258) Thiopurine-induced leukopenia in inflammatory bowel disease ( 29923122) Trunk fat mass ( 28552196)
Interacting Genes		14 interacting genes: APP ARF1 ARF5 ARF6 BTK CADPS CASP3 KRAS NEDD4 PIP5KL1 PLD1 PLD2 RHOU TEC	15 interacting genes: C17orf67 DMD DNAJC5 DRD2 FAM161A FAM9B KIAA1549 LUC7L2 PIP5K1A SDCBP SHFL TCL1A TTLL10 ZNF572 ZNF688
Entrez ID		8394	8618
HPRD ID		04470	05236
Ensembl ID		ENSG00000143398	ENSG00000163618
Uniprot IDs		A6PW57 Q99755	F1T0E5 Q9ULU8
PDB IDs			1WI1
Enriched GO Terms of Interacting Partners?
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