RGS20 and NECTIN3

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		RGS20	NECTIN3
Description		regulator of G protein signaling 20	nectin cell adhesion molecule 3
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Trans-Golgi Network Plasma Membrane	Plasma Membrane Cell-cell Junction Adherens Junction Axon Dendrite Apical Junction Complex Cell-cell Contact Zone Hippocampal Mossy Fiber To CA3 Synapse Integral Component Of Postsynaptic Density Membrane
	Molecular Function	GTPase Activity GTPase Activator Activity Protein Binding	Protein Binding Signaling Receptor Activity Protein Homodimerization Activity Cell Adhesion Molecule Binding
	Biological Process	G Protein-coupled Receptor Signaling Pathway Regulation Of G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Signal Transduction Positive Regulation Of GTPase Activity	Lens Morphogenesis In Camera-type Eye Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Spermatid Development Fertilization Adherens Junction Organization Retina Morphogenesis In Camera-type Eye Establishment Of Protein Localization To Plasma Membrane Protein Localization To Cell Junction
Pathways		G alpha (i) signalling events G alpha (i) signalling events G alpha (z) signalling events G alpha (z) signalling events	Adherens junctions interactions Nectin/Necl trans heterodimerization
Drugs
Diseases
GWAS		Cerebrospinal fluid beta-site APP cleaving enzyme levels ( 29751835) Serum uric acid levels ( 29559957) Urinary albumin-to-creatinine ratio ( 26631737)	Feeling hurt ( 29500382)
Interacting Genes		34 interacting genes: ABHD17A ADRB2 AQP1 CATSPER1 CRCT1 CREB5 FASLG GLRX3 GNAI1 GNAI2 GNAI3 GNAO1 GNAZ HOXA1 HSPD1 INS KIF1A KLHL38 KRTAP4-2 KRTAP5-6 KRTAP5-9 LCE1B LCE2A LCE2D LCE3E LCE4A MAPKBP1 NECTIN3 OSTM1 OTX1 PTGER3 PTPMT1 STMN2 TBC1D16	13 interacting genes: AFDN KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP4-2 NECTIN1 NECTIN2 NOTCH2NLA PARD3 PVR RGS20 TIGIT
Entrez ID		8601	25945
HPRD ID		06225	08454
Ensembl ID		ENSG00000147509	ENSG00000177707
Uniprot IDs		B3KSW4 H9NIM5 O76081	Q9NQS3
PDB IDs			4FOM
Enriched GO Terms of Interacting Partners?
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