MYOZ1 and TCAP

Number of citations of the paper that reports this interaction (PubMedID 10984498)
36

Data Source:
HPRD (in vitro)

		MYOZ1	TCAP
Description		myozenin 1	titin-cap
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Actin Cytoskeleton Z Disc Pseudopodium	Cytosol Z Disc I Band
	Molecular Function	Actin Binding Protein Serine/threonine Phosphatase Inhibitor Activity Protein Binding Telethonin Binding FATZ Binding	Protein Binding Structural Constituent Of Muscle Protein Binding, Bridging Titin Binding BMP Binding Ion Channel Binding FATZ Binding Titin Z Domain Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Skeletal Muscle Tissue Development Myofibril Assembly Negative Regulation Of Phosphoprotein Phosphatase Activity Negative Regulation Of Skeletal Muscle Tissue Regeneration Skeletal Muscle Fiber Adaptation Sarcomere Organization Negative Regulation Of Calcineurin-NFAT Signaling Cascade	Somitogenesis Skeletal Muscle Contraction Cardiac Muscle Hypertrophy Adult Heart Development Cardiac Muscle Hypertrophy In Response To Stress Muscle Filament Sliding Skeletal Muscle Thin Filament Assembly Skeletal Muscle Myosin Thick Filament Assembly Otic Vesicle Formation Response To Muscle Stretch Detection Of Muscle Stretch Sarcomere Organization Cardiac Muscle Fiber Development Sarcomerogenesis Detection Of Mechanical Stimulus Cardiac Myofibril Assembly Cardiac Muscle Tissue Morphogenesis Cardiac Muscle Contraction Protein-containing Complex Assembly
Pathways			Striated Muscle Contraction
Drugs
Diseases			Limb-girdle muscular dystrophy (LGMD)
GWAS		Atrial fibrillation ( 30061737)	Alcohol consumption ( 31358974) Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Pancreatic ductal adenocarcinoma ( 30541042) Ulcerative colitis ( 20228799)
Interacting Genes		14 interacting genes: ACTN1 ACTN2 ACTN4 APP BRCA1 FLNC GRB2 LDB3 MAGEA11 PNKP PRKAA2 TCAP TRIM55 TRIM63	17 interacting genes: ANKRD2 ATXN1 CRK FAS FYN HSPB2 LHX4 MDM2 MSTN MYOZ1 MYOZ3 PDPK1 RELA SIVA1 TRIM55 TRIM63 TTN
Entrez ID		58529	8557
HPRD ID		05725	05133
Ensembl ID		ENSG00000177791	ENSG00000173991
Uniprot IDs		Q9NP98	A2TDC0 O15273
PDB IDs			1YA5 2F8V
Enriched GO Terms of Interacting Partners?
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