AP3B1 and BUB1

Number of citations of the paper that reports this interaction (PubMedID 12419313)
12

Data Source:
HPRD (two hybrid)

		AP3B1	BUB1
Description		adaptor related protein complex 3 subunit beta 1	BUB1 mitotic checkpoint serine/threonine kinase
Image		No pdb structure
GO Annotations	Cellular Component	Cell Lysosomal Membrane Golgi Apparatus Membrane AP-3 Adaptor Complex Clathrin Adaptor Complex Clathrin-coated Vesicle Membrane Synapse Axon Cytoplasm	Kinetochore Condensed Chromosome Kinetochore Condensed Nuclear Chromosome Kinetochore Condensed Nuclear Chromosome Outer Kinetochore Nucleoplasm Cytosol Membrane
	Molecular Function	Protein Phosphatase Binding GTP-dependent Protein Binding	Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding
	Biological Process	Protein Targeting To Lysosome Intracellular Protein Transport Blood Coagulation Anterograde Axonal Transport Synaptic Vesicle Budding From Endosome Vesicle-mediated Transport Melanosome Organization Antigen Processing And Presentation, Exogenous Lipid Antigen Via MHC Class Ib Anterograde Synaptic Vesicle Transport Positive Regulation Of NK T Cell Differentiation	Protein Phosphorylation Apoptotic Process Regulation Of Sister Chromatid Cohesion Mitotic Cell Cycle Checkpoint Mitotic Spindle Assembly Checkpoint Cell Proliferation Viral Process Cell Division Meiotic Sister Chromatid Cohesion, Centromeric Regulation Of Chromosome Segregation
Pathways		Golgi Associated Vesicle Biogenesis Signaling by BRAF and RAF fusions	Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases		Hermansky-Pudlak syndrome (HPS)
GWAS		FEV1 ( 30804560) Insulin resistance/response ( 21901158) Lung function (FEV1) ( 30061609) Lung function (FVC) ( 30061609 30804560) Metabolite levels ( 23823483) Triglycerides ( 26780889) Type 2 diabetes ( 31049640)
Interacting Genes		19 interacting genes: AP3D1 AP3S2 ARF1 ARF5 ARF6 ARR3 ATM ATR BUB1 BUB1B CLTC CSNK1A1 CXADR FCGR2B GKAP1 RNGTT SLC30A3 SSBP2 ZER1	18 interacting genes: AP1B1 AP2B1 AP3B1 AP4B1 APC ARIH2 BUB3 CDC20 CDK1 CRK EIF4EBP1 FBXO7 HDAC1 KNL1 PLK1 RAE1 RDH12 SVIL
Entrez ID		8546	699
HPRD ID		04551	03907
Ensembl ID		ENSG00000132842	ENSG00000169679
Uniprot IDs		A0A0S2Z5J4 O00203	B4DYG2 O43683
PDB IDs			2LAH 4A1G 4QPM 4R8Q 5DMZ 6F7B
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
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