AP3B1 and ARF1

Number of citations of the paper that reports this interaction (PubMedID 11926829)
15

Data Source:
HPRD (in vitro)

		AP3B1	ARF1
Description		adaptor related protein complex 3 subunit beta 1	ADP ribosylation factor 1
Image		No pdb structure
GO Annotations	Cellular Component	Cell Lysosomal Membrane Golgi Apparatus Membrane AP-3 Adaptor Complex Clathrin Adaptor Complex Clathrin-coated Vesicle Membrane Synapse Axon Cytoplasm	Golgi Membrane Cell Cytoplasm Late Endosome Peroxisomal Membrane Trans-Golgi Network Cytosol Plasma Membrane Focal Adhesion Postsynaptic Density Sarcomere COPI-coated Vesicle Cell Leading Edge Protein-containing Complex Neuron Projection Perinuclear Region Of Cytoplasm Extracellular Exosome Glutamatergic Synapse
	Molecular Function	Protein Phosphatase Binding GTP-dependent Protein Binding	Magnesium Ion Binding RNA Binding GTPase Activity Protein Binding GTP Binding GDP Binding Protein Domain Specific Binding Phospholipase D Activator Activity
	Biological Process	Protein Targeting To Lysosome Intracellular Protein Transport Blood Coagulation Anterograde Axonal Transport Synaptic Vesicle Budding From Endosome Vesicle-mediated Transport Melanosome Organization Antigen Processing And Presentation, Exogenous Lipid Antigen Via MHC Class Ib Anterograde Synaptic Vesicle Transport Positive Regulation Of NK T Cell Differentiation	Regulation Of Receptor Internalization Phosphatidylinositol Biosynthetic Process Cellular Copper Ion Homeostasis Intracellular Protein Transport Actin Filament Organization Vesicle-mediated Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Regulation Of Arp2/3 Complex-mediated Actin Nucleation Very-low-density Lipoprotein Particle Assembly Interleukin-12-mediated Signaling Pathway Positive Regulation Of Catalytic Activity Positive Regulation Of Endocytosis Positive Regulation Of Calcium Ion-dependent Exocytosis Regulation Of Defense Response To Virus By Virus Positive Regulation Of Protein Secretion Golgi To Transport Vesicle Transport Long-term Synaptic Depression Positive Regulation Of Dendritic Spine Development Synaptic Vesicle Budding Dendritic Spine Organization Lysosomal Membrane Organization Cellular Response To Virus Postsynaptic Actin Cytoskeleton Organization Positive Regulation Of Sodium Ion Transmembrane Transport Positive Regulation Of Late Endosome To Lysosome Transport Positive Regulation Of ER To Golgi Vesicle-mediated Transport Regulation Of Phospholipid Metabolic Process Mitotic Cleavage Furrow Ingression
Pathways		Golgi Associated Vesicle Biogenesis Signaling by BRAF and RAF fusions	Synthesis of PIPs at the plasma membrane Synthesis of PIPs at the Golgi membrane Nef Mediated CD4 Down-regulation trans-Golgi Network Vesicle Budding MHC class II antigen presentation Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic Intra-Golgi traffic Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
Drugs			1,3-Propandiol Guanosine-3'-Monophosphate-5'-Diphosphate Guanosine-5'-Triphosphate Guanosine-5'-Diphosphate Brefeldin A Myristic acid Glycerin
Diseases		Hermansky-Pudlak syndrome (HPS)
GWAS		FEV1 ( 30804560) Insulin resistance/response ( 21901158) Lung function (FEV1) ( 30061609) Lung function (FVC) ( 30061609 30804560) Metabolite levels ( 23823483) Triglycerides ( 26780889) Type 2 diabetes ( 31049640)	Adolescent idiopathic scoliosis ( 31417091)
Interacting Genes		19 interacting genes: AP3D1 AP3S2 ARF1 ARF5 ARF6 ARR3 ATM ATR BUB1 BUB1B CLTC CSNK1A1 CXADR FCGR2B GKAP1 RNGTT SLC30A3 SSBP2 ZER1	45 interacting genes: AGAP1 AGAP2 AP1B1 AP1G1 AP3B1 AP3D1 AP3S2 AP4E1 AP4M1 ARFGAP1 ARFIP1 ARFIP2 ARHGAP21 ASAP1 ASAP2 CHRM3 COPB1 COPE COPG1 CYTH1 CYTH2 EEF1G GGA1 GGA2 GGA3 GORAB GOSR2 HTR2A INSR KDELR1 MDM4 NOA1 NPM1 PICK1 PIP5K1A PLD1 PLD2 PLEKHA8 PLIN2 RALA SCYL1 TMED10 TMED2 TMEM106A WBP11
Entrez ID		8546	375
HPRD ID		04551	00054
Ensembl ID		ENSG00000132842	ENSG00000143761
Uniprot IDs		A0A0S2Z5J4 O00203	A0A024R3Q0 P84077
PDB IDs			1HUR 1RE0 1U81 3O47 4HMY 6CM9 6CRI 6D83 6D84 6DFF 6FAE
Enriched GO Terms of Interacting Partners?
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