LMO4 and NHLH1

Number of citations of the paper that reports this interaction (PubMedID 12878195)
21

Data Source:
HPRD (in vitro, in vivo)

		LMO4	NHLH1
Description		LIM domain only 4	nescient helix-loop-helix 1
Image			No pdb structure
GO Annotations	Cellular Component	Transcription Factor Complex Cell Leading Edge	Nuclear Chromatin Nucleus
	Molecular Function	Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Transcription Factor Binding Metal Ion Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Dimerization Activity
	Biological Process	Neural Tube Closure Ventricular Septum Development Transcription By RNA Polymerase II Ventral Spinal Cord Interneuron Differentiation Spinal Cord Motor Neuron Differentiation Spinal Cord Association Neuron Differentiation Regulation Of Cell Migration Negative Regulation Of Protein Complex Assembly Positive Regulation Of Kinase Activity Regulation Of Cell Fate Specification Positive Regulation Of Transcription By RNA Polymerase II Thymus Development Regulation Of Cell Activation	Regulation Of Transcription By RNA Polymerase II Central Nervous System Development Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS		Angiotensin-converting enzyme inhibitor intolerance ( 28030426) Breast cancer ( 27354352) Eosinophil counts ( 29403010) Gait rhythm ( 26219847) Glaucoma (primary open-angle) ( 29891935) Photic sneeze reflex ( 27182965) Prostate-specific antigen levels ( 28139693) Response to TNF antagonist treatment ( 18615156) Resting heart rate ( 27798624) White blood cell count (basophil) ( 29403010) White blood cell types ( 21738478)
Interacting Genes		53 interacting genes: AMOT AMOTL2 BANP BRCA1 CALCOCO2 CCDC102B CEP170P1 CSNK2B DDB1 DEAF1 ERCC6L GABPB1 GADD45A GOLGA2 GRHL2 GSK3B ITSN1 KANK2 KIAA1958 KIF3B KPNA1 KRT15 KRT31 KRT40 LDB1 LDB2 MERTK MTA1 NFYC NHLH1 NONO PDE4DIP PITPNB PLK1 PPARG RBBP8 RBPMS RPS6KA6 SEC24D SMAD4 SMAD9 TCF21 TCF4 TFIP11 TINAGL1 TLE5 TNFSF11 TP53BP2 TSEN15 VPS52 ZBTB43 ZNF397 ZNF675	10 interacting genes: CENPP CSRP3 HIVEP1 INO80E LMO1 LMO2 LMO4 PIM1 PSME2 TCF3
Entrez ID		8543	4807
HPRD ID		09122	01212
Ensembl ID		ENSG00000143013	ENSG00000171786
Uniprot IDs		P61968	Q02575 Q5T203
PDB IDs		2L4Z
Enriched GO Terms of Interacting Partners?
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