DGKZ and SNX27

Number of citations of the paper that reports this interaction (PubMedID 17351151)
32

Data Source:
HPRD (two hybrid, in vivo)

		DGKZ	SNX27
Description		diacylglycerol kinase zeta	sorting nexin 27
Image
GO Annotations	Cellular Component	Nucleus Cytoplasm Plasma Membrane Postsynaptic Density Nuclear Speck Lamellipodium Glutamatergic Synapse	Immunological Synapse Nucleoplasm Endosome Early Endosome Cytosol Retromer Complex Early Endosome Membrane WASH Complex
	Molecular Function	NAD+ Kinase Activity Diacylglycerol Kinase Activity Protein Binding ATP Binding Kinase Activity Metal Ion Binding	Protein Binding Phosphatidylinositol-3-phosphate Binding Phosphatidylinositol Binding
	Biological Process	Phosphatidic Acid Biosynthetic Process Protein Kinase C-activating G Protein-coupled Receptor Signaling Pathway Cell Migration Platelet Activation Intracellular Signal Transduction Diacylglycerol Metabolic Process Glycerolipid Metabolic Process Lipid Phosphorylation Regulation Of Synaptic Transmission, Glutamatergic Positive Regulation Of 1-phosphatidylinositol-4-phosphate 5-kinase Activity	Establishment Of Natural Killer Cell Polarity Intracellular Protein Transport Signal Transduction Endosome To Lysosome Transport Endosomal Transport Retrograde Transport, Endosome To Plasma Membrane
Pathways		Effects of PIP2 hydrolysis
Drugs
Diseases
GWAS		Alzheimer's disease or fasting glucose levels (pleiotropy) ( 30805717) Autism spectrum disorder or schizophrenia ( 28540026) Immunoglobulin A ( 20694011) Reaction time ( 29844566) Schizophrenia ( 28991256 29483656)	Body mass index ( 26426971)
Interacting Genes		19 interacting genes: DMD HRAS LEPR MAPK6 PLCG1 POLR2M PRKCA RASGRP1 RB1 RBL1 RBL2 SAT1 SNTA1 SNTB1 SNTB2 SNTG1 SNX27 SRC TP53	10 interacting genes: AKT2 APP DGKZ HLCS PNPLA3 PTEN RPS6KA1 SELP SLC2A1 VPS26A
Entrez ID		8525	81609
HPRD ID		03260	11591
Ensembl ID		ENSG00000149091	ENSG00000143376
Uniprot IDs		Q13574	A0A2R8Y8A7 Q96L92
PDB IDs		5ELQ	4HAS 5ZN9 6SAK
Enriched GO Terms of Interacting Partners?
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