UBASH3B and DOC2A

Number of citations of the paper that reports this interaction (PubMedID 26186194)
367

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, two hybrid)

		UBASH3B	DOC2A
Description		ubiquitin associated and SH3 domain containing B	double C2 domain alpha
Image
GO Annotations	Cellular Component	Nucleus Cytoplasm	Nucleoplasm Nucleolus Lysosome Cell Junction Neuron Projection Extrinsic Component Of Synaptic Vesicle Membrane
	Molecular Function	Protein Tyrosine Phosphatase Activity Protein Binding Ubiquitin Protein Ligase Binding Identical Protein Binding Phosphoprotein Binding	Calcium Ion Binding Protein Binding Calcium-dependent Phospholipid Binding
	Biological Process	Negative Regulation Of Protein Kinase Activity Negative Regulation Of Signal Transduction Peptidyl-tyrosine Dephosphorylation Collagen-activated Tyrosine Kinase Receptor Signaling Pathway Collagen-activated Signaling Pathway Regulation Of Protein Binding Regulation Of Osteoclast Differentiation Negative Regulation Of Osteoclast Differentiation Negative Regulation Of Bone Resorption Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Platelet Aggregation Negative Regulation Of Platelet Aggregation	Chemical Synaptic Transmission Nervous System Development Synaptic Vesicle Exocytosis Regulation Of Calcium Ion-dependent Exocytosis Spontaneous Neurotransmitter Secretion
Pathways
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Blood urea nitrogen levels ( 31152163) Cholesterol, total ( 24097068 25961943 20686565) Chronotype ( 30696823) Diastolic blood pressure ( 30224653) Eye length ( 30174134) HDL cholesterol ( 24097068 20686565) Multiple sclerosis and HDL levels (pleiotropy) ( 26920376) Pemphigus vulgaris ( 29857070) Stroke ( 26089329) Systolic blood pressure ( 30578418) Total cholesterol levels ( 28334899)	Autism spectrum disorder or schizophrenia ( 28540026) Body fat distribution (arm fat ratio) ( 30664634) Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Height ( 28552196) Schizophrenia ( 28991256 25056061 29483656)
Interacting Genes		27 interacting genes: CBL CBLB CUL3 DAZAP2 DMRT3 DOC2A FAM168A JAK2 KHDRBS1 MAP3K1 PKP4 PRKN RCHY1 RNF41 SHC1 SLC25A48 SPRY2 SYK UBB UBC UBE2C UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2H VPS37B	5 interacting genes: DYNLT1 RAP1GDS1 STXBP1 UBASH3B UNC13B
Entrez ID		84959	8448
HPRD ID		16463	05195
Ensembl ID		ENSG00000154127	ENSG00000149927
Uniprot IDs		Q8TF42	Q14183
PDB IDs		2CPW 2E5K 5VR6 5W5G	4MJJ
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?