PPM1D and BEX2

Number of citations of the paper that reports this interaction (PubMedID 25640309)
5

Data Source:
BioGRID (two hybrid)

		PPM1D	BEX2
Description		protein phosphatase, Mg2+/Mn2+ dependent 1D	brain expressed X-linked 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol	Nucleus Cytoplasm
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Serine/threonine Phosphatase Activity Magnesium-dependent Protein Serine/threonine Phosphatase Activity Protein Binding Metal Ion Binding Mitogen-activated Protein Kinase Binding	Protein Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle DNA Methylation Chromatin Silencing Transcription Initiation From RNA Polymerase II Promoter Protein Phosphorylation Protein Dephosphorylation Negative Regulation Of Cell Proliferation Cellular Response To Starvation Response To Radiation Response To Bacterium DNA Damage Response, Signal Transduction By P53 Class Mediator Peptidyl-threonine Dephosphorylation Negative Regulation Of Gene Expression, Epigenetic	Apoptotic Process Cell Cycle Regulation Of Apoptotic Process Regulation Of Cell Cycle
Pathways		Transcriptional regulation by RUNX2
Drugs
Diseases
GWAS		Blood urea nitrogen levels ( 31152163)
Interacting Genes		25 interacting genes: ATP6V1A BEX2 CASZ1 CHEK2 DIRAS3 DKK3 EPSTI1 ERRFI1 GLCE H3-3A H3C1 ITIH5 KDM1A LYPD3 MAPK11 MDM2 MRC2 NAT2 NCL NSD3 OSGIN1 RHOBTB2 RPL5 TP53 UBC	35 interacting genes: AURKA BCAR3 BLZF1 BRMS1 CALCOCO2 CCDC85B CEP70 FGFR2 FSD2 KRT15 KRT31 KRT38 KRT40 KRTAP10-8 KRTAP4-12 KRTAP5-9 LMO2 LZTS2 MAGEA11 MAGEA4 MIPOL1 MKRN3 NECAB2 OMP PIK3CA PNMA1 PPM1D PRDM14 PTPN11 SSX2IP TRAF1 TRAF2 TRIM27 TRIM42 ZDHHC17
Entrez ID		8493	84707
HPRD ID		05482	06484
Ensembl ID		ENSG00000170836	ENSG00000133134
Uniprot IDs		A0A0S2Z4M2 O15297	Q9BXY8
PDB IDs
Enriched GO Terms of Interacting Partners?
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