PTPN5 and CXCL9

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		PTPN5	CXCL9
Description		protein tyrosine phosphatase non-receptor type 5	C-X-C motif chemokine ligand 9
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Endoplasmic Reticulum Membrane Integral Component Of Membrane	Extracellular Region Extracellular Space Cell External Side Of Plasma Membrane
	Molecular Function	Phosphotyrosine Residue Binding Protein Tyrosine Phosphatase Activity Protein Binding	Cytokine Activity Protein Binding Chemokine Activity CXCR Chemokine Receptor Binding CXCR3 Chemokine Receptor Binding
	Biological Process	Protein Dephosphorylation Peptidyl-tyrosine Dephosphorylation Cellular Response To Cytokine Stimulus	Chemotaxis Defense Response Inflammatory Response Immune Response Cellular Defense Response Signal Transduction G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Cell-cell Signaling Neutrophil Chemotaxis Leukocyte Chemotaxis Regulation Of Cell Proliferation Positive Regulation Of Myoblast Differentiation Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Defense Response To Virus Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Chemokine-mediated Signaling Pathway Cellular Response To Lipopolysaccharide Positive Regulation Of Myoblast Fusion
Pathways		Interleukin-37 signaling	Chemokine receptors bind chemokines G alpha (i) signalling events
Drugs
Diseases
GWAS		Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin) ( 23648065) Myopia ( 27182965)	Blood protein levels ( 28240269) Hippocampal volume ( 29274321) Neonatal cytokine/chemokine levels (fetal genetic effect) ( 30134952)
Interacting Genes		14 interacting genes: CCNQ CUL5 CXCL9 FYN MAPK1 MAPK3 MOB1A PRKN SAAL1 SNX4 TERF1 TMEM51 VTI1B ZBTB5	10 interacting genes: BMF CCR3 CXCR3 DPP4 FBXO7 KASH5 PAX8 PTPN5 SFTPC SYNE4
Entrez ID		84867	4283
HPRD ID		01472	03416
Ensembl ID		ENSG00000110786	ENSG00000138755
Uniprot IDs		B7Z2F8 P54829 Q86TL3	Q07325
PDB IDs		2BIJ 2BV5 2CJZ 5OVR 5OVX 5OW1 6H8R
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?