CXCL9 and CXCR3

Number of citations of the paper that reports this interaction (PubMedID 12782716)
162

Data Source:
HPRD (in vitro, in vivo)

		CXCL9	CXCR3
Description		C-X-C motif chemokine ligand 9	C-X-C motif chemokine receptor 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cell External Side Of Plasma Membrane	Cell Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane
	Molecular Function	Cytokine Activity Protein Binding Chemokine Activity CXCR Chemokine Receptor Binding CXCR3 Chemokine Receptor Binding	Chemokine Receptor Activity Protein Binding C-C Chemokine Receptor Activity C-X-C Chemokine Receptor Activity Chemokine Binding C-C Chemokine Binding Identical Protein Binding
	Biological Process	Chemotaxis Defense Response Inflammatory Response Immune Response Cellular Defense Response Signal Transduction G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Cell-cell Signaling Neutrophil Chemotaxis Leukocyte Chemotaxis Regulation Of Cell Proliferation Positive Regulation Of Myoblast Differentiation Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Defense Response To Virus Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Chemokine-mediated Signaling Pathway Cellular Response To Lipopolysaccharide Positive Regulation Of Myoblast Fusion	Angiogenesis Regulation Of Leukocyte Migration Apoptotic Process Chemotaxis Inflammatory Response Immune Response Cell Adhesion Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration T Cell Chemotaxis Calcium-mediated Signaling Regulation Of Cell Adhesion Cell Chemotaxis Chemokine-mediated Signaling Pathway
Pathways		Chemokine receptors bind chemokines G alpha (i) signalling events	Chemokine receptors bind chemokines G alpha (i) signalling events
Drugs
Diseases
GWAS		Blood protein levels ( 28240269) Hippocampal volume ( 29274321) Neonatal cytokine/chemokine levels (fetal genetic effect) ( 30134952)
Interacting Genes		10 interacting genes: BMF CCR3 CXCR3 DPP4 FBXO7 KASH5 PAX8 PTPN5 SFTPC SYNE4	6 interacting genes: CXCL10 CXCL11 CXCL13 CXCL9 FATE1 PF4
Entrez ID		4283	2833
HPRD ID		03416	02936
Ensembl ID		ENSG00000138755	ENSG00000186810
Uniprot IDs		Q07325	P49682
PDB IDs
Enriched GO Terms of Interacting Partners?
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