ZGPAT and DHX15

Number of citations of the paper that reports this interaction (PubMedID 26871637)
108

Data Source:
BioGRID (two hybrid)

		ZGPAT	DHX15
Description		zinc finger CCCH-type and G-patch domain containing	DEAH-box helicase 15
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GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Plasma Membrane	Intracellular Nucleus Nucleoplasm Spliceosomal Complex U12-type Spliceosomal Complex Nucleolus Nuclear Speck U2-type Post-mRNA Release Spliceosomal Complex
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Metal Ion Binding	RNA Binding RNA Helicase Activity Double-stranded RNA Binding Protein Binding ATP Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Epidermal Growth Factor-activated Receptor Activity Negative Regulation Of Transcription, DNA-templated	MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Response To Toxic Substance Response To Alkaloid
Pathways			mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) C-reactive protein levels ( 30388399) Crohn's disease ( 28067908) Diverticular disease ( 30177863) Estimated glomerular filtration rate ( 31152163 31015462) Inflammatory bowel disease ( 28067908 23128233) Lung function (FEV1) ( 28166213) Prostate cancer ( 31562322 23535732) Ulcerative colitis ( 28067908 21297633)	Myopia (pathological) ( 23049088) Pulmonary emphysema ( 24383474) Sense of smell ( 26632684)
Interacting Genes		39 interacting genes: AIMP2 AMOTL2 BEND5 BLZF1 CCDC33 CCDC57 CCNDBP1 CDCA7L CDR2 CEP57L1 CEP70 CTNNA1 DHX15 DVL2 DYDC1 FAM9B GOLGA2 IHO1 IKZF3 KIFC3 KRT15 KRT40 LDOC1 LZTS2 MID2 MIPOL1 NEBL PHC2 PRPF3 SPAG5 SSX2IP STAC3 TFIP11 TLE5 TP53BP2 TRIM27 TRIM54 UPF2 ZBTB8A	13 interacting genes: APBB1 DDX42 NKAP PIN1 PRPF40A RBM17 SPOP TRA2A UBC WBP4 YWHAB YWHAG ZGPAT
Entrez ID		84619	1665
HPRD ID		15736	04553
Ensembl ID		ENSG00000197114	ENSG00000109606
Uniprot IDs		A0A0S2Z5X3 Q8N5A5	O43143
PDB IDs		4II1	5XDR 6ID1
Enriched GO Terms of Interacting Partners?
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