PARD6B and RHOJ

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid, affinity chromatography technology, affinity chromatography technology)

		PARD6B	RHOJ
Description		par-6 family cell polarity regulator beta	ras homolog family member J
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Plasma Membrane Bicellular Tight Junction Cell Cortex Apical Plasma Membrane Protein-containing Complex Extracellular Exosome	Cytoplasm Cytosol Cytoskeleton Plasma Membrane Cell Cortex Cytoplasmic Vesicle Cell Projection Intracellular Membrane-bounded Organelle Extracellular Exosome
	Molecular Function	Protein Kinase C Binding Protein Binding Rho GTPase Binding	GTPase Activity Protein Binding GTP Binding Protein Kinase Binding
	Biological Process	Cell-cell Junction Assembly Centrosome Cycle Establishment Or Maintenance Of Cell Polarity Axonogenesis Regulation Of Cell Migration Cell Division Regulation Of Cellular Localization Protein-containing Complex Assembly Bicellular Tight Junction Assembly	Angiogenesis Endocytosis Actin Filament Organization Establishment Or Maintenance Of Cell Polarity Rho Protein Signal Transduction Regulation Of Cell Shape Regulation Of Endothelial Cell Migration Cell Migration Cell Projection Assembly Actin Cytoskeleton Organization Cortical Cytoskeleton Organization Regulation Of Actin Cytoskeleton Organization Regulation Of Small GTPase Mediated Signal Transduction Retina Vasculature Morphogenesis In Camera-type Eye Positive Regulation Of Cell Migration Involved In Sprouting Angiogenesis Regulation Of Sprouting Angiogenesis
Pathways		Tight junction interactions	Rho GTPase cycle
Drugs
Diseases
GWAS		Bipolar disorder ( 21771265)	Endometriosis ( 28881265) Heel bone mineral density ( 30598549) Metabolite levels ( 23823483)
Interacting Genes		24 interacting genes: APP ARAP3 CDC42 CEP76 GMCL1 GOLGA2 HTRA1 MPP5 PARD3 PARD3B PARD6A PNMA1 PRKCG PRKCI PRKCZ RAC1 RHOJ RHOQ SIAH1 TCP10L3 WDR83 YWHAB YWHAH YWHAZ	20 interacting genes: ACVR1 ADAMTSL4 BHLHE40 BLZF1 BMPR1B CDC42 CDC42EP1 DOCK10 DOCK8 MEOX2 PAK1 PAK6 PARD6B SMAD2 SMAD4 SSX3 TGFBR1 TRIP10 WAS WASL
Entrez ID		84612	57381
HPRD ID		18703	09632
Ensembl ID		ENSG00000124171	ENSG00000126785
Uniprot IDs		Q9BYG5	A0A024R692 Q7Z513 Q9H4E5
PDB IDs
Enriched GO Terms of Interacting Partners?
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