MAML2 and NOTCH4

  • Number of citations of the paper that reports this interaction (PubMedID 12370315)
  • 71
  • Data Source:
  • HPRD (in vivo)

MAML2

NOTCH4

Description mastermind like transcriptional coactivator 2 notch receptor 4
Image No pdb structure No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203)
  • Corneal astigmatism ( 23322567)
  • Height ( 23456168)
  • Influenza A (H1N1) severity ( 26379185)
  • Keratoconus ( 31855235)
  • Methadone dose in opioid dependence ( 28115739)
  • Non-glioblastoma glioma ( 28346443)
  • Pelvic organ prolapse ( 26545240)
  • Response to chemotherapy in breast cancer hypertensive cases (cumulative dose) (bevacizumab) ( 25117820)
  • Response to treatment for acute lymphoblastic leukemia ( 19176441)
  • Ulcerative colitis ( 28067908 23128233)
  • Waist-to-hip circumference ratio (alcohol intake interaction) ( 23192594)
  • Advanced glycation end-product levels ( 26083729)
  • Age-related macular degeneration ( 22694956)
  • Aspartate aminotransferase levels ( 29403010)
  • Asthma ( 21804548 31619474)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Bipolar disorder ( 31043756)
  • Blood protein levels ( 28240269)
  • Blood protein levels in cardiovascular risk ( 28369058)
  • Chronic hepatitis B infection ( 25802187)
  • Circulating myeloperoxidase levels (serum) ( 23620142)
  • Clozapine-induced agranulocytosis/granulocytopenia in treatment-resistant schizophrenia ( 26876947)
  • Colorectal cancer ( 30529582)
  • Crohn's disease ( 23266558)
  • Epstein-Barr virus immune response (EBNA-1) ( 23326239)
  • Food antigen IgG levels ( 24962563)
  • HIV-1 control ( 20041166)
  • Inflammatory bowel disease ( 28067908)
  • Iron status biomarkers (iron levels) ( 28334935)
  • Joint mobility (Beighton score) ( 27182965)
  • Longevity ( 30294719)
  • Lung cancer ( 28604730)
  • Lung cancer in ever smokers ( 28604730)
  • Lupus nephritis in systemic lupus erythematosus ( 24925725)
  • Migraine ( 27322543)
  • Mixed cryoglobulinemia vasculitis in chronic hepatitis C infection ( 25030430)
  • Obesity-related traits ( 23251661)
  • Objective response to lithium treatment in bipolar disorder ( 26503763)
  • Prostate cancer ( 23535732)
  • Reticulocyte fraction of red cells ( 27863252)
  • Sarcoidosis (non-Lofgren's syndrome without extrapulmonary manifestations) ( 26651848)
  • Schizophrenia ( 19571808 30285260 23894747)
  • Squamous cell lung carcinoma ( 28604730)
  • Systemic lupus erythematosus ( 21408207)
  • Systemic sclerosis ( 21779181)
  • Takayasu arteritis ( 25604533)
  • Type 1 diabetes and autoimmune thyroid diseases ( 25936594)
  • Ulcerative colitis ( 24837172 28067908)
  • Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500)
  • Waist-to-hip ratio adjusted for body mass index ( 28448500)
Interacting Genes 7 interacting genes: CREBBP CTBP1 DIABLO NOTCH1 NOTCH2 NOTCH3 NOTCH4 14 interacting genes: DLL4 EGFL7 ELOC FBXW7 MAML1 MAML2 MAML3 NEU1 PSEN1 PSEN2 RBPJ SMAD2 SMAD3 SMAD4
Entrez ID 84441 4855
HPRD ID 09608 01290
Ensembl ID ENSG00000184384 ENSG00000204301
Uniprot IDs Q8IZL2 A0A1U9X983 Q99466
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?