THOC3 and MLKL

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

		THOC3	MLKL
Description		THO complex 3	mixed lineage kinase domain like pseudokinase
Image		No pdb structure
GO Annotations	Cellular Component	Transcription Export Complex THO Complex Part Of Transcription Export Complex Nuclear Chromosome, Telomeric Region Nucleoplasm Nuclear Speck	Cytoplasm Cytosol Plasma Membrane
	Molecular Function	RNA Binding	Protein Kinase Activity Protein Binding ATP Binding Protein Kinase Binding Protein-containing Complex Binding
	Biological Process	RNA Export From Nucleus MRNA Export From Nucleus RNA Splicing MRNA 3'-end Processing Viral MRNA Export From Host Cell Nucleus	Protein Phosphorylation Cell Surface Receptor Signaling Pathway Protein Homotrimerization Necroptotic Process
Pathways		Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA 3'-end processing RNA Polymerase II Transcription Termination	TRP channels RIPK1-mediated regulated necrosis
Drugs
Diseases
GWAS		Chronotype ( 30696823)	Testicular germ cell tumor ( 23666239)
Interacting Genes		4 interacting genes: BRCA1 DDX39B MLKL TK1	5 interacting genes: ANAPC11 CDK1 NDUFB7 RAD18 THOC3
Entrez ID		84321	197259
HPRD ID		09497	08752
Ensembl ID		ENSG00000051596	ENSG00000168404
Uniprot IDs		Q96J01	Q8NB16
PDB IDs			2MSV 4M67 4MWI 5KNJ 5KO1 6BWK 6D74
Enriched GO Terms of Interacting Partners?
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