WDR83 and PARD6A

Number of citations of the paper that reports this interaction (PubMedID 23439680)
12

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		WDR83	PARD6A
Description		WD repeat domain 83	par-6 family cell polarity regulator alpha
Image		No pdb structure
GO Annotations	Cellular Component	Spliceosomal Complex Endosome Membrane Catalytic Step 2 Spliceosome	Ruffle Nucleus Centrosome Cytosol Plasma Membrane Bicellular Tight Junction Cell Cortex Apical Plasma Membrane Centriolar Satellite
	Molecular Function	Protein Binding	Protein Kinase C Binding Protein Binding Transcription Factor Binding Rho GTPase Binding GTP-dependent Protein Binding
	Biological Process	MAPK Cascade RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome Response To Hypoxia	Negative Regulation Of Protein Phosphorylation Centrosome Cycle Establishment Or Maintenance Of Cell Polarity Transforming Growth Factor Beta Receptor Signaling Pathway Viral Process Cell-cell Junction Maintenance Positive Regulation Of Protein Secretion Cell Division Wnt Signaling Pathway, Planar Cell Polarity Pathway Regulation Of Cellular Localization Bicellular Tight Junction Assembly Positive Regulation Of Protein Localization To Centrosome
Pathways		MAP2K and MAPK activation	TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) Tight junction interactions Asymmetric localization of PCP proteins
Drugs
Diseases
GWAS			Obesity-related traits ( 23251661) Schizophrenia ( 25056061 29483656)
Interacting Genes		17 interacting genes: BAG2 CRB3 CRK EGLN3 GPKOW HNRNPH2 HSPB1 KDM1A KEAP1 LSM3 PARD6A PARD6B PCBP2 RACK1 SAP30BP SF1 TOE1	26 interacting genes: APP ATP5MG CDC42 CDH5 CRB3 DVL2 ECT2 GLS MAP2K5 MARK2 MARK4 PARD3 PARD6B PLCB1 PLCB3 PRKCG PRKCH PRKCI PRKCZ RAC1 RHOQ TCP10L3 TGFBR1 WDR83 YWHAH YWHAZ
Entrez ID		84292	50855
HPRD ID		14730	06316
Ensembl ID		ENSG00000123154	ENSG00000102981
Uniprot IDs		Q9BRX9	Q9NPB6
PDB IDs			1WMH
Enriched GO Terms of Interacting Partners?
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