ING5 and GCSH

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ING5	GCSH
Description		inhibitor of growth family member 5	glycine cleavage system protein H
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm MOZ/MORF Histone Acetyltransferase Complex	Mitochondrion Mitochondrial Matrix Glycine Cleavage Complex
	Molecular Function	Chromatin Binding Protein Binding Methylated Histone Binding Metal Ion Binding	Aminomethyltransferase Activity Protein Binding
	Biological Process	DNA Replication Protein Acetylation Negative Regulation Of Cell Proliferation Positive Regulation Of Apoptotic Process Histone H3 Acetylation Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Growth Regulation Of Signal Transduction By P53 Class Mediator Positive Regulation Of Apoptotic Signaling Pathway	Glycine Catabolic Process Protein Lipoylation Glycine Decarboxylation Via Glycine Cleavage System
Pathways		HATs acetylate histones Regulation of TP53 Activity through Acetylation	Glyoxylate metabolism and glycine degradation Glycine degradation
Drugs			Glycine 6-(Hydroxyethyldithio)-8-(Aminomethylthio)Octanoic Acid Dihydrolipoic Acid
Diseases			Nonketotic hyperglycinemia; Glycine encephalopathy (GCE)
GWAS		Asthma (adult onset) ( 31036433) Asthma (childhood onset) ( 31036433)	Glycine levels ( 31070104 30837465) Metabolite levels (small molecules and protein measures) ( 27005778) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		35 interacting genes: APC APLP1 ARFIP2 BARD1 C3orf62 CCDC33 CDCA7L CDK2 CDKN1A CEP126 CEP44 DEUP1 EP300 FAM118B GCSH HAP1 HGS HTT ICA1 IKZF3 JADE2 KRT40 KRTAP10-7 KXD1 MBIP MCM6 MEST NAV2 PCM1 PRMT5 SMARCE1 TADA3 TAF1D TP53 VIM	4 interacting genes: ING5 NMI SFI1 ZBTB16
Entrez ID		84289	2653
HPRD ID		16348	01998
Ensembl ID		ENSG00000168395	ENSG00000140905
Uniprot IDs		A0A1B0GW41 Q8WYH8	P23434
PDB IDs		3C6W 5ME8 5MTO
Enriched GO Terms of Interacting Partners?
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