SPATC1L and PARN

Number of citations of the paper that reports this interaction (PubMedID 15231747)
56

Data Source:
HPRD (two hybrid)

		SPATC1L	PARN
Description		spermatogenesis and centriole associated 1 like	poly(A)-specific ribonuclease
Image		No pdb structure
GO Annotations	Cellular Component	Cellular_component Centrosome	Nucleus Nucleolus Cytoplasm Cytosol Nuclear Speck
	Molecular Function	Molecular_function Protein Binding	3'-5'-exoribonuclease Activity RNA Binding MRNA 3'-UTR Binding Nuclease Activity Poly(A)-specific Ribonuclease Activity Protein Binding Protein Kinase Binding Cation Binding Metal Ion Binding Telomerase RNA Binding
	Biological Process	Biological_process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Nuclear-transcribed MRNA Poly(A) Tail Shortening Box H/ACA SnoRNA 3'-end Processing Female Gamete Generation RNA Modification MiRNA Catabolic Process Positive Regulation Of Telomere Maintenance Via Telomerase Regulation Of MRNA Stability Positive Regulation Of Telomerase Activity Polyadenylation-dependent SnoRNA 3'-end Processing RNA Phosphodiester Bond Hydrolysis, Exonucleolytic Telomerase RNA Stabilization NcRNA Deadenylation Regulation Of Telomerase RNA Localization To Cajal Body
Pathways			ATF4 activates genes in response to endoplasmic reticulum stress Deadenylation of mRNA KSRP (KHSRP) binds and destabilizes mRNA
Drugs
Diseases
GWAS			Age at voice drop ( 27182965) Height ( 25429064) Male-pattern baldness ( 27182965) Menarche (age at onset) ( 27182965) Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid) ( 24823311) Plasma omega-6 polyunsaturated fatty acid levels (gamma-linolenic acid) ( 24823311) Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid) ( 24823311)
Interacting Genes		13 interacting genes: ARL4A ARMC7 FSD2 IKZF1 KRTAP5-9 LZTS2 PARN PHC2 PNMA1 PPP1CC SIAH1 TCF4 TRIM27	6 interacting genes: KHSRP MAPKAPK2 MPHOSPH6 MPP6 SPATC1L SUMO2
Entrez ID		84221	5073
HPRD ID		10753	07250
Ensembl ID		ENSG00000160284	ENSG00000140694
Uniprot IDs		Q9H0A9	A0A494C0Q2 A0A494C1K5 B3KN69 O95453
PDB IDs			2A1R 2A1S 3CTR
Enriched GO Terms of Interacting Partners?
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