PARN and SPATC1L

Number of citations of the paper that reports this interaction (PubMedID 15231747)
56

Data Source:
HPRD (two hybrid)

		PARN	SPATC1L
Description		poly(A)-specific ribonuclease	spermatogenesis and centriole associated 1 like
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleolus Cytoplasm Cytosol Nuclear Speck	Cellular_component Centrosome
	Molecular Function	3'-5'-exoribonuclease Activity RNA Binding MRNA 3'-UTR Binding Nuclease Activity Poly(A)-specific Ribonuclease Activity Protein Binding Protein Kinase Binding Cation Binding Metal Ion Binding Telomerase RNA Binding	Molecular_function Protein Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Nuclear-transcribed MRNA Poly(A) Tail Shortening Box H/ACA SnoRNA 3'-end Processing Female Gamete Generation RNA Modification MiRNA Catabolic Process Positive Regulation Of Telomere Maintenance Via Telomerase Regulation Of MRNA Stability Positive Regulation Of Telomerase Activity Polyadenylation-dependent SnoRNA 3'-end Processing RNA Phosphodiester Bond Hydrolysis, Exonucleolytic Telomerase RNA Stabilization NcRNA Deadenylation Regulation Of Telomerase RNA Localization To Cajal Body	Biological_process
Pathways		ATF4 activates genes in response to endoplasmic reticulum stress Deadenylation of mRNA KSRP (KHSRP) binds and destabilizes mRNA
Drugs
Diseases
GWAS		Age at voice drop ( 27182965) Height ( 25429064) Male-pattern baldness ( 27182965) Menarche (age at onset) ( 27182965) Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid) ( 24823311) Plasma omega-6 polyunsaturated fatty acid levels (gamma-linolenic acid) ( 24823311) Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid) ( 24823311)
Interacting Genes		6 interacting genes: KHSRP MAPKAPK2 MPHOSPH6 MPP6 SPATC1L SUMO2	13 interacting genes: ARL4A ARMC7 FSD2 IKZF1 KRTAP5-9 LZTS2 PARN PHC2 PNMA1 PPP1CC SIAH1 TCF4 TRIM27
Entrez ID		5073	84221
HPRD ID		07250	10753
Ensembl ID		ENSG00000140694	ENSG00000160284
Uniprot IDs		A0A494C0Q2 A0A494C1K5 B3KN69 O95453	Q9H0A9
PDB IDs		2A1R 2A1S 3CTR
Enriched GO Terms of Interacting Partners?
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