ANKRD27 and VAMP7

Number of citations of the paper that reports this interaction (PubMedID 19745841)
36

Data Source:
BioGRID (pull down, affinity chromatography technology)

		ANKRD27	VAMP7
Description		ankyrin repeat domain 27	vesicle associated membrane protein 7
Image
GO Annotations	Cellular Component	Lysosome Early Endosome Late Endosome Cytosol Plasma Membrane Membrane Transport Vesicle Cytoplasmic Vesicle Membrane Melanosome Neuron Projection Tubular Endosome	Cell Cytoplasm Lysosomal Membrane Endoplasmic Reticulum Membrane Trans-Golgi Network Plasma Membrane Cell Surface Membrane Lamellipodium Cell Junction Secretory Granule Filopodium Integral Component Of Synaptic Vesicle Membrane Clathrin-coated Vesicle Membrane Secretory Granule Membrane Phagocytic Vesicle Membrane Platelet Alpha Granule Pseudopodium SNARE Complex Late Endosome Membrane Azurophil Granule Membrane Neuron Projection Intracellular Membrane-bounded Organelle Apical Part Of Cell Phagocytic Vesicle Perinuclear Region Of Cytoplasm Extracellular Exosome Hippocampal Mossy Fiber To CA3 Synapse
	Molecular Function	SNARE Binding Guanyl-nucleotide Exchange Factor Activity GTPase Activator Activity Protein Binding Rab GTPase Binding	SNARE Binding SNAP Receptor Activity Protein Binding Syntaxin Binding
	Biological Process	Protein Transport Negative Regulation Of SNARE Complex Assembly Endosome To Melanosome Transport Positive Regulation Of GTPase Activity Early Endosome To Late Endosome Transport Neuron Projection Morphogenesis Positive Regulation Of Dendrite Morphogenesis Retrograde Transport, Endosome To Plasma Membrane	Exocytosis ER To Golgi Vesicle-mediated Transport Post-Golgi Vesicle-mediated Transport Vesicle Fusion Phagocytosis, Engulfment Endosome To Lysosome Transport Vesicle-mediated Transport Calcium Ion Regulated Exocytosis Triglyceride Transport SNARE Complex Assembly Golgi To Plasma Membrane Protein Transport Eosinophil Degranulation Neutrophil Degranulation Natural Killer Cell Degranulation Vesicle Transport Along Microtubule Vesicle Fusion With Golgi Apparatus Positive Regulation Of Dendrite Morphogenesis Membrane Organization Autophagosome Maturation Regulation Of Protein Targeting To Vacuolar Membrane Positive Regulation Of Histamine Secretion By Mast Cell
Pathways		RAB GEFs exchange GTP for GDP on RABs	trans-Golgi Network Vesicle Budding Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis Interleukin-12 signaling
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Eosinophilic esophagitis ( 25407941) Major depressive disorder ( 23377640) Red cell distribution width ( 27863252 28957414)
Interacting Genes		5 interacting genes: RAB40A RAB40B RAB40C SMAD1 VAMP7	11 interacting genes: AGFG1 ANKRD27 AP3D1 DNAJC5 SNAP23 SNAP25 SNAP29 STX1A STX3 STX4 STX7
Entrez ID		84079	6845
HPRD ID		10650	02084
Ensembl ID		ENSG00000105186	ENSG00000124333
Uniprot IDs		Q96NW4	A0A024R061 A0A024R074 P51809
PDB IDs		4B93 4CYM 4CZ2	2DMW
Enriched GO Terms of Interacting Partners?
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