ANKRD27

Description		ankyrin repeat domain 27
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GO Annotations	Cellular Component	Lysosome Early Endosome Late Endosome Cytosol Plasma Membrane Membrane Transport Vesicle Cytoplasmic Vesicle Membrane Melanosome Neuron Projection Tubular Endosome
	Molecular Function	SNARE Binding Guanyl-nucleotide Exchange Factor Activity GTPase Activator Activity Protein Binding Rab GTPase Binding
	Biological Process	Protein Transport Negative Regulation Of SNARE Complex Assembly Endosome To Melanosome Transport Positive Regulation Of GTPase Activity Early Endosome To Late Endosome Transport Neuron Projection Morphogenesis Positive Regulation Of Dendrite Morphogenesis Retrograde Transport, Endosome To Plasma Membrane
Pathways		RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Eosinophilic esophagitis ( 25407941) Major depressive disorder ( 23377640) Red cell distribution width ( 27863252 28957414)
Interacting Genes		5 interacting genes: RAB40A RAB40B RAB40C SMAD1 VAMP7
Entrez ID		84079
HPRD ID		10650
Ensembl ID		ENSG00000105186
Uniprot IDs		Q96NW4
PDB IDs		4B93 4CYM 4CZ2
Enriched GO Terms of Interacting Partners?
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