CAPZA1 and S100A1

Number of citations of the paper that reports this interaction (PubMedID 9803314)
8

Data Source:
HPRD (in vitro)

		CAPZA1	S100A1
Description		capping actin protein of muscle Z-line subunit alpha 1	S100 calcium binding protein A1
Image
GO Annotations	Cellular Component	Extracellular Region Cytosol Cytoskeleton F-actin Capping Protein Complex Actin Cytoskeleton Actin Cortical Patch Extracellular Exosome WASH Complex	Extracellular Region Nucleus Sarcoplasmic Reticulum Z Disc M Band Protein-containing Complex Neuron Projection
	Molecular Function	Actin Binding Protein Binding Cadherin Binding Actin Filament Binding	Calcium Ion Binding Protein Binding Identical Protein Binding Protein Homodimerization Activity S100 Protein Binding Calcium-dependent Protein Binding ATPase Binding
	Biological Process	ER To Golgi Vesicle-mediated Transport Blood Coagulation Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Actin Cytoskeleton Organization Cell Junction Assembly Interleukin-12-mediated Signaling Pathway Innate Immune Response Barbed-end Actin Filament Capping Protein-containing Complex Assembly	Negative Regulation Of Transcription By RNA Polymerase II Toll-like Receptor Signaling Pathway Regulation Of Heart Contraction Substantia Nigra Development Intracellular Signal Transduction Positive Regulation Of Nitric-oxide Synthase Activity Positive Regulation Of Voltage-gated Calcium Channel Activity Positive Regulation Of Sprouting Angiogenesis
Pathways		MHC class II antigen presentation HSP90 chaperone cycle for steroid hormone receptors (SHR) COPI-mediated anterograde transport COPI-independent Golgi-to-ER retrograde traffic Advanced glycosylation endproduct receptor signaling Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation Factors involved in megakaryocyte development and platelet production Factors involved in megakaryocyte development and platelet production	Regulation of TLR by endogenous ligand
Drugs			Olopatadine
Diseases
GWAS		Blood pressure ( 21572416) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Chronotype ( 30696823) Diastolic blood pressure ( 26390057 27841878 28739976 27618452 30487518) Height ( 25282103) Hypertension ( 30487518) Intraocular pressure ( 29617998 29785010) Mean arterial pressure ( 30487518) Platelet count ( 27863252) Systolic blood pressure ( 27841878 28739976 27618452 30487518) Total cholesterol levels ( 30275531)
Interacting Genes		7 interacting genes: ACTB CD2AP HSPA8 S100A1 S100B SH3KBP1 UCHL5	27 interacting genes: ACTA1 AGER ANXA6 ATP2A2 BIK CACYBP CAPZA1 CEP20 DES FKBP4 GFAP GJA1 MDM2 NIF3L1 PGM1 PLB1 PLEKHF2 PLN PPID PYGM REL RYR1 S100A2 S100A4 S100B S100P SYN1
Entrez ID		829	6271
HPRD ID		03347	01489
Ensembl ID		ENSG00000116489	ENSG00000160678
Uniprot IDs		P52907	A0A0S2Z4H2 P23297
PDB IDs		1MQ1 1MWN	2L0P 2LHL 2LLS 2LLT 2LLU 2LP2 2LP3 2LUX 2M3W 5K89
Enriched GO Terms of Interacting Partners?
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