ZRSR2 and U2AF2

Number of citations of the paper that reports this interaction (PubMedID 9237760)
44

Data Source:
HPRD (in vitro, in vivo, two hybrid)

		ZRSR2	U2AF2
Description		zinc finger CCCH-type, RNA binding motif and serine/arginine rich 2	U2 small nuclear RNA auxiliary factor 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Spliceosomal Complex U12-type Spliceosomal Complex U2AF	Commitment Complex Prp19 Complex Nucleus Nucleoplasm Spliceosomal Complex Nuclear Speck U2-type Prespliceosome U2AF
	Molecular Function	Protein Binding Pre-mRNA 3'-splice Site Binding Metal Ion Binding	RNA Binding Protein Binding Poly-pyrimidine Tract Binding Enzyme Binding Pre-mRNA 3'-splice Site Binding C2H2 Zinc Finger Domain Binding
	Biological Process	Spliceosomal Complex Assembly MRNA Splicing, Via Spliceosome RNA Splicing	MRNA Splicing, Via Spliceosome MRNA Processing RNA Export From Nucleus MRNA Export From Nucleus MRNA 3'-end Processing Negative Regulation Of Protein Ubiquitination Positive Regulation Of RNA Splicing Negative Regulation Of MRNA Splicing, Via Spliceosome
Pathways		mRNA Splicing - Minor Pathway	Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs
Diseases
GWAS			Menopause (age at onset) ( 26414677)
Interacting Genes		8 interacting genes: APP CLK2 SDCBP2 SRSF1 SRSF2 SSX2IP U2AF1 U2AF2	47 interacting genes: APBB1 ATXN1 BEND7 CCAR1 CHERP CHIC2 CPSF7 DACH1 DDX6 DPPA2 DVL2 EPB41 GEMIN2 GLIS2 HLA-DMA IL7R KHDC4 KHDRBS3 LURAP1 MAP1B OTUB2 PIN1 POLR2A PRPF3 PRPF40A PUF60 QKI RBFOX2 RBM39 RBM4 SAP30BP SCAF11 SF1 SMAD5 SNRPA SRPK1 SRPK2 SRSF1 SRSF11 SUGP1 TCERG1 THAP1 TLE5 TOP1 U2AF1 WT1 ZRSR2
Entrez ID		8233	11338
HPRD ID		02068	01872
Ensembl ID		ENSG00000169249	ENSG00000063244
Uniprot IDs		Q15696	P26368
PDB IDs			1JMT 1O0P 1OPI 1U2F 2G4B 2HZC 2M0G 2U2F 2YH0 2YH1 3VAF 3VAG 3VAH 3VAI 3VAJ 3VAK 3VAL 3VAM 4FXW 4TU7 4TU8 4TU9 5EV1 5EV2 5EV3 5EV4 5W0G 5W0H
Enriched GO Terms of Interacting Partners?
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