RAB1B and SMARCC2

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		RAB1B	SMARCC2
Description		RAB1B, member RAS oncogene family	SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Endomembrane System Transport Vesicle Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Phagophore Assembly Site Membrane Perinuclear Region Of Cytoplasm Extracellular Exosome	Nuclear Chromatin Nucleoplasm SWI/SNF Complex Protein-containing Complex NpBAF Complex NBAF Complex
	Molecular Function	GTPase Activity Protein Binding GTP Binding	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding Transcription Coactivator Activity Protein Binding Nucleosomal DNA Binding Histone Binding
	Biological Process	Autophagosome Assembly Intracellular Protein Transport ER To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To ER Virion Assembly Rab Protein Signal Transduction Post-translational Protein Modification COPII Vesicle Coating Establishment Of Endothelial Intestinal Barrier Positive Regulation Of Glycoprotein Metabolic Process Regulation Of Autophagosome Assembly	Nucleosome Disassembly Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Nervous System Development ATP-dependent Chromatin Remodeling Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated
Pathways		Golgi Cisternae Pericentriolar Stack Reorganization Golgi Cisternae Pericentriolar Stack Reorganization COPII-mediated vesicle transport COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs	RMTs methylate histone arginines RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972 31043756)	Asthma ( 31619474)
Interacting Genes		10 interacting genes: APP CHM GDI1 GOLGA2 MICAL1 MICAL3 MICALCL RUSC2 SMARCC2 TOMM40L	25 interacting genes: ARF6 ARRB2 ATXN1 ATXN1L BAZ1B CSNK2A1 EWSR1 FUS GATA1 IFTAP ITCH ITSN1 KLF1 MCPH1 NOVA1 PEX14 PHYHIP POLR2C RAB1B RELB SP1 SRGAP3 TAF15 TERF1 TERF2IP
Entrez ID		81876	6601
HPRD ID		11469	03437
Ensembl ID		ENSG00000174903	ENSG00000139613
Uniprot IDs		Q9H0U4	A0A024RB22 F8VXC8 Q8TAQ2
PDB IDs		3JZA 3NKV 4HLQ 4I1O 5O74 5SZH 5SZK
Enriched GO Terms of Interacting Partners?
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