FAM83D and DYNC1I1

Number of citations of the paper that reports this interaction (PubMedID 28514442)
199

Data Source:
BioGRID (affinity chromatography technology, two hybrid)

		FAM83D	DYNC1I1
Description		family with sequence similarity 83 member D	dynein cytoplasmic 1 intermediate chain 1
Image			No pdb structure
GO Annotations	Cellular Component	Cell Cytoplasm Cytosol Microtubule Cytoskeleton Intercellular Bridge Mitotic Spindle Mitotic Spindle Pole	Kinetochore Condensed Chromosome Kinetochore Spindle Pole Cell Nucleus Cytoplasm Cytosol Cytoplasmic Dynein Complex Microtubule Vesicle Cytoplasmic Ribonucleoprotein Granule Perinuclear Region Of Cytoplasm Recycling Endosome
	Molecular Function	Protein Binding Microtubule Binding Kinesin Binding Protein Kinase Binding	Motor Activity Microtubule Motor Activity Protein Binding Microtubule Binding Spectrin Binding Dynein Light Chain Binding Dynein Heavy Chain Binding
	Biological Process	Epithelial To Mesenchymal Transition Cell Proliferation Cell Migration Regulation Of TOR Signaling Regulation Of Protein Catabolic Process Cell Division Metaphase Plate Congression Regulation Of ERK1 And ERK2 Cascade Protein Localization To Mitotic Spindle Positive Regulation Of Cell Cycle G1/S Phase Transition	ER To Golgi Vesicle-mediated Transport Microtubule-based Movement Transport Along Microtubule Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Vesicle Transport Along Microtubule Positive Regulation Of ATP-dependent Microtubule Motor Activity, Plus-end-directed
Pathways			Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal MHC class II antigen presentation Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion HSP90 chaperone cycle for steroid hormone receptors (SHR) RHO GTPases Activate Formins COPI-mediated anterograde transport COPI-independent Golgi-to-ER retrograde traffic Mitotic Prometaphase HCMV Early Events Aggrephagy Aggrephagy EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Alcohol dependence or chronic alcoholic pancreatitis or alcohol-related liver cirrhosis ( 28714907) Huntington's disease progression ( 28642124)	Dementia and core Alzheimer's disease neuropathologic changes ( 25188341) Heel bone mineral density ( 30598549) Hip circumference adjusted for BMI ( 28552196) Immune reponse to smallpox (secreted IL-10) ( 22610502) Knee osteoarthritis ( 27696742) Multisite chronic pain ( 31194737) Obesity-related traits ( 23251661)
Interacting Genes		6 interacting genes: CEP250 CSNK1E DYNC1I1 GADD45A GSK3B PRMT1	32 interacting genes: ANXA7 BICD1 CADM4 CDKN1A DNM2 DYNLL1 DYNLL2 DYNLRB1 DYNLT1 DYNLT3 EMILIN1 FAM110A FAM83D FBP1 GRB7 GSK3B KAT7 MCC NAGK NDEL1 NUDT21 NUP214 PIN1 RAP1GAP RCC1 RUNDC3B SMN1 STAU1 TAOK1 TK1 TRIM58 WDCP
Entrez ID		81610	1780
HPRD ID		12744	04798
Ensembl ID		ENSG00000101447	ENSG00000158560
Uniprot IDs		Q9H4H8	A4D1I7 O14576 Q8N542
PDB IDs		5E0L 5E0M
Enriched GO Terms of Interacting Partners?
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