CEP70 and KANK2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		CEP70	KANK2
Description		centrosomal protein 70	KN motif and ankyrin repeat domains 2
Image		No pdb structure
GO Annotations	Cellular Component	Centrosome Cytosol	Cytoplasm Mitochondrion
	Molecular Function	Protein Binding Identical Protein Binding Gamma-tubulin Binding	Protein Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Microtubule Cytoskeleton Organization Ciliary Basal Body-plasma Membrane Docking	Negative Regulation Of Transcription By RNA Polymerase II Apoptotic Process Negative Regulation Of Cell Proliferation Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway Regulation Of Rho Protein Signal Transduction Negative Regulation Of Programmed Cell Death Negative Regulation Of Vitamin D Receptor Signaling Pathway Kidney Epithelium Development Glomerular Visceral Epithelial Cell Migration Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways		Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs
Diseases
GWAS		Exhaled carbon monoxide levels in smokers with chronic obstructive pulmonary disease ( 29631575) Male-pattern baldness ( 28196072)	Cholesterol, total ( 26780889) Coronary artery disease ( 29212778) HDL cholesterol ( 23505323) High light scatter reticulocyte count ( 27863252) High light scatter reticulocyte percentage of red cells ( 27863252) Immature fraction of reticulocytes ( 27863252) Intraocular pressure ( 31959993) Red cell distribution width ( 27863252 28957414) Reticulocyte count ( 27863252) Reticulocyte fraction of red cells ( 27863252)
Interacting Genes		144 interacting genes: ABT1 AKAP17A ARHGEF3 ATP5PO ATXN7 BARD1 BEX2 BRMS1 BYSL C1orf35 C7orf25 C8orf33 CARD9 CCDC85B CDC73 CDCA7L CEP57L1 CFAP53 CLPB COIL DAZAP2 DDX41 DDX6 DNAJB11 ELOA ELOA2 EMD EMP1 ENKD1 ERCC3 FAM118B FAM124A FAM133A FAM13C FAM161A FAM214B GATAD2B GCC1 GPATCH2L GPATCH4 GPX7 HAUS1 HDAC6 HMGB4 HSPD1 IK IQCE KANK2 KANSL1 KAT7 KDM1A KRT31 LAMTOR5 LENG1 LENG8 LIN37 MCM10 MEST METTL17 MFAP1 MRPL44 NIPSNAP3A NKAP NKAPD1 NOL12 NOP2 NRIP1 NUSAP1 PAM16 PIBF1 PIMREG PLA2G2A PPFIA1 PPIG PPP1R16B PRKRIP1 PRPF31 PSMA1 RBM10 RCOR3 RHPN1 RNF6 RPL13 SERPINH1 SETD5 SFR1 SH2D4A SLU7 SMARCE1 SNRPD2 SRGN SSX3 STK25 STMN2 SUV39H1 SUV39H2 SYT17 SYTL4 SYTL5 TAF1D TEAD4 TRIM29 TRIM42 TSFM TSGA10IP TSHZ3 TTC25 TTLL10 TXLNB UTP11 UTP14A UTP25 WT1 YJU2 ZBTB16 ZBTB24 ZBTB49 ZBTB8A ZCCHC10 ZFC3H1 ZGPAT ZNF136 ZNF148 ZNF169 ZNF227 ZNF239 ZNF266 ZNF302 ZNF329 ZNF366 ZNF408 ZNF410 ZNF417 ZNF426 ZNF439 ZNF490 ZNF555 ZNF557 ZNF572 ZNF578 ZNF587 ZNF607 ZNF688 ZSCAN12	23 interacting genes: ABI3 CCDC33 CEP70 CSNK2A1 DYNLL1 EIF4E FHL2 GOLGA2 GPSM1 IHO1 LMO1 LMO2 LMO4 MAGEB4 MOB1A NCOA1 NOS3 PSEN1 SRPK2 STAC TLE5 TXLNA VPS52
Entrez ID		80321	25959
HPRD ID		16779	12463
Ensembl ID		ENSG00000114107	ENSG00000197256
Uniprot IDs		A0A140VJG2 B7Z2D2 Q8NHQ1	Q63ZY3
PDB IDs			4HBD 5YBV
Enriched GO Terms of Interacting Partners?
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