RNF128 and APPBP2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		RNF128	APPBP2
Description		ring finger protein 128	amyloid beta precursor protein binding protein 2
Image			No pdb structure
GO Annotations	Cellular Component	Late Endosome Endoplasmic Reticulum Golgi Apparatus Cytosol Cytoskeleton Integral Component Of Membrane Perinuclear Region Of Cytoplasm	Nucleus Cytoplasm Microtubule Microtubule Associated Complex Cytoplasmic Vesicle Membrane
	Molecular Function	Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	Microtubule Motor Activity Protein Binding
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Protein Deubiquitination Regulation Of Protein Stability Negative Regulation Of Cytokine Biosynthetic Process Protein Localization To Lysosome Positive Regulation Of Protein Catabolic Process In The Vacuole	Intracellular Protein Transport Intracellular Transport
Pathways		Ub-specific processing proteases Ovarian tumor domain proteases
Drugs
Diseases
GWAS		Alcoholic chronic pancreatitis ( 28754779) Creatinine levels ( 31015462) Estimated glomerular filtration rate ( 31015462)	Waist-hip ratio ( 28552196)
Interacting Genes		14 interacting genes: APPBP2 CD151 CD40LG CD81 CEP76 OTUB1 TBK1 TP53 UBE2D1 UBE2E1 UBE2H UBE2I UBE2N UBE2T	81 interacting genes: - AHCY AIM2 AK3 ANKRD10 APP AR ARMCX5 C1orf50 C6orf226 CALM3 CCDC85C CCNL1 CDK16 CHMP5 CIBAR1 CLCN1 CNTFR COL24A1 CORO2B CREB3 CSNK1G2 CTC1 CYBA DCD DHRS2 DPEP1 EID3 ERO1A FAM107A FSTL1 FXYD7 GALNT3 GCSAM GP9 GSTP1 H2AC15 HIPK4 HSPA4 KIF6 KLF11 KLHL35 LANCL2 LONRF3 LUC7L2 LUZP4 MFSD3 MLLT3 MUL1 NFYA NPRL3 PCSK5 PI4KAP2 PPP1R8 PRKAA2 PRKACB PYROXD2 RASSF5 RNF128 RNF34 RRS1 SELENOI SELENOV SLC22A6 SLC25A23 SNX5 ST8SIA5 SYNRG SYT11 TAF11 TAFA4 TBL3 TCF25 UBE2R2 UGGT2 WAS WDR24 WNT5B ZC3H10 ZCCHC12 ZNF747
Entrez ID		79589	10513
HPRD ID		02340	05616
Ensembl ID		ENSG00000133135	ENSG00000062725
Uniprot IDs		Q8TEB7	A0A024QZ47 Q92624
PDB IDs		3ICU
Enriched GO Terms of Interacting Partners?
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