APPBP2 and CTC1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		APPBP2	CTC1
Description		amyloid beta precursor protein binding protein 2	CST telomere replication complex component 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Microtubule Microtubule Associated Complex Cytoplasmic Vesicle Membrane	Nuclear Chromosome, Telomeric Region Nucleus CST Complex
	Molecular Function	Microtubule Motor Activity Protein Binding	Single-stranded DNA Binding Protein Binding Telomeric DNA Binding G-rich Strand Telomeric DNA Binding
	Biological Process	Intracellular Protein Transport Intracellular Transport	Telomere Maintenance Cellular Response To DNA Damage Stimulus Regulation Of G2/M Transition Of Mitotic Cell Cycle Telomere Maintenance Via Telomere Lengthening Telomere Capping Negative Regulation Of Telomere Maintenance Via Telomerase Multicellular Organism Growth Positive Regulation Of DNA Replication Positive Regulation Of Fibroblast Proliferation Spleen Development Thymus Development Bone Marrow Development Hematopoietic Stem Cell Proliferation Replicative Senescence
Pathways			Telomere C-strand synthesis initiation
Drugs
Diseases
GWAS		Waist-hip ratio ( 28552196)	Bipolar disorder ( 28115744) Telomere length ( 23001564)
Interacting Genes		81 interacting genes: - AHCY AIM2 AK3 ANKRD10 APP AR ARMCX5 C1orf50 C6orf226 CALM3 CCDC85C CCNL1 CDK16 CHMP5 CIBAR1 CLCN1 CNTFR COL24A1 CORO2B CREB3 CSNK1G2 CTC1 CYBA DCD DHRS2 DPEP1 EID3 ERO1A FAM107A FSTL1 FXYD7 GALNT3 GCSAM GP9 GSTP1 H2AC15 HIPK4 HSPA4 KIF6 KLF11 KLHL35 LANCL2 LONRF3 LUC7L2 LUZP4 MFSD3 MLLT3 MUL1 NFYA NPRL3 PCSK5 PI4KAP2 PPP1R8 PRKAA2 PRKACB PYROXD2 RASSF5 RNF128 RNF34 RRS1 SELENOI SELENOV SLC22A6 SLC25A23 SNX5 ST8SIA5 SYNRG SYT11 TAF11 TAFA4 TBL3 TCF25 UBE2R2 UGGT2 WAS WDR24 WNT5B ZC3H10 ZCCHC12 ZNF747	2 interacting genes: APPBP2 TPP1
Entrez ID		10513	80169
HPRD ID		05616	07980
Ensembl ID		ENSG00000062725	ENSG00000178971
Uniprot IDs		A0A024QZ47 Q92624	Q2NKJ3
PDB IDs			5W2L
Enriched GO Terms of Interacting Partners?
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